2023
Precise, pragmatic and inclusive: the modern era of oncology clinical trials
Grant M, Goldberg S. Precise, pragmatic and inclusive: the modern era of oncology clinical trials. Nature Medicine 2023, 29: 1908-1909. PMID: 37524954, DOI: 10.1038/s41591-023-02466-6.Peer-Reviewed Original Research
2018
Intraoperative cerebral oximetry-based management for optimizing perioperative outcomes: a meta-analysis of randomized controlled trials
Zorrilla-Vaca A, Healy R, Grant M, Joshi B, Rivera-Lara L, Brown C, Mirski M. Intraoperative cerebral oximetry-based management for optimizing perioperative outcomes: a meta-analysis of randomized controlled trials. Journal Canadien D'anesthésie 2018, 65: 529-542. PMID: 29427259, DOI: 10.1007/s12630-018-1065-7.Peer-Reviewed Original ResearchConceptsPostoperative cognitive dysfunctionIntensive care unitIntraoperative cerebral oximetryCerebral oximetryPostoperative deliriumIncidence of POCDProspective clinical trialsOverall hospital LOSPredictors of outcomeGoogle Scholar databasesHospital LOSPurposeAlthough evidenceHospital lengthPerioperative outcomesPostoperative outcomesSecondary outcomesPrimary outcomeCare unitClinical outcomesIntraoperative managementLarge RCTsCochrane LibraryClinical trialsCognitive dysfunctionObservational study
2017
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review
Wick E, Grant M, Wu C. Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review. JAMA Surgery 2017, 152: 691-697. PMID: 28564673, DOI: 10.1001/jamasurg.2017.0898.Peer-Reviewed Original ResearchConceptsNonsteroidal anti-inflammatory agentsAnti-inflammatory agentsERAS pathwayPostoperative bleedingN-methyl-D-aspartate (NMDA) classMultimodal analgesia approachGlutamate receptor antagonistsCurrent opioid epidemicComplex surgical proceduresAnalgesic regimensOpioid consumptionLess opioidsMultimodal analgesiaNarcotic analgesiaNonopioid analgesicsHospital dischargeMost patientsPain managementRegional analgesiaSurgery pathwayReceptor antagonistClinical trialsOpioid epidemicEffective adjunctSurgical care