2024
Protective mechanical ventilation in critically ill patients after surgery
Zorrilla-Vaca A, Arevalo J, Grant M. Protective mechanical ventilation in critically ill patients after surgery. Current Opinion In Critical Care 2024, 30: 679-683. PMID: 39503212, DOI: 10.1097/mcc.0000000000001215.Peer-Reviewed Original ResearchIntensive care unitVentilator-induced lung injuryLung protective strategyCritically ill patientsMechanical ventilationCare unitLung injurySurgical patientsFast-track extubation protocolOpen-lung ventilation strategyIll patientsRisk of ventilator-induced lung injuryHigh-flow nasal cannulaHigh-risk surgical patientsOpen lung ventilationOperating roomNoninvasive ventilation supportProtective mechanical ventilationPositive-end expiratory pressureAcute lung injuryMechanically ventilated patientsStandard of careThoracic surgeryNasal cannulaRetrospective study
2019
Perioperative Dextrose Infusion and Postoperative Nausea and Vomiting
Zorrilla-Vaca A, Marmolejo-Posso D, Stone A, Li J, Grant MC. Perioperative Dextrose Infusion and Postoperative Nausea and Vomiting. Anesthesia & Analgesia 2019, Publish Ahead of Print: &na;. PMID: 30649067, DOI: 10.1213/ane.0000000000004019.Peer-Reviewed Original ResearchConceptsPostoperative nauseaDextrose infusionAntiemetic administrationGlucose levelsPlasma glucose monitoringPostoperative antiemetic administrationRescue antiemetic requirementsFurther prospective trialsPostanesthesia care unitSerum glucose levelsPlasma glucose levelsSignificant reductionAntiemetic requirementsPostoperative hyperglycemiaProspective trialSecondary outcomesPostoperative infusionPrimary outcomeCare unitCochrane LibraryUse of dextroseNauseaVomitingInfusionSignificant association
2018
Intraoperative cerebral oximetry-based management for optimizing perioperative outcomes: a meta-analysis of randomized controlled trials
Zorrilla-Vaca A, Healy R, Grant M, Joshi B, Rivera-Lara L, Brown C, Mirski M. Intraoperative cerebral oximetry-based management for optimizing perioperative outcomes: a meta-analysis of randomized controlled trials. Journal Canadien D'anesthésie 2018, 65: 529-542. PMID: 29427259, DOI: 10.1007/s12630-018-1065-7.Peer-Reviewed Original ResearchConceptsPostoperative cognitive dysfunctionIntensive care unitIntraoperative cerebral oximetryCerebral oximetryPostoperative deliriumIncidence of POCDProspective clinical trialsOverall hospital LOSPredictors of outcomeGoogle Scholar databasesHospital LOSPurposeAlthough evidenceHospital lengthPerioperative outcomesPostoperative outcomesSecondary outcomesPrimary outcomeCare unitClinical outcomesIntraoperative managementLarge RCTsCochrane LibraryClinical trialsCognitive dysfunctionObservational study