2021
Transesophageal Echocardiography in Patients Undergoing Coronary Artery Bypass Graft Surgery
Metkus T, Thibault D, Grant M, Badhwar V, Jacobs J, Lawton J, O'Brien S, Thourani V, Wegermann Z, Zwischenberger B, Higgins R. Transesophageal Echocardiography in Patients Undergoing Coronary Artery Bypass Graft Surgery. Journal Of The American College Of Cardiology 2021, 78: 112-122. PMID: 33957241, PMCID: PMC8876254, DOI: 10.1016/j.jacc.2021.04.064.Peer-Reviewed Original ResearchConceptsIntraoperative transesophageal echocardiographyHigh-risk patientsTransesophageal echocardiographyCABG patientsOperative mortalityValve proceduresCoronary artery bypass graft surgeryThoracic Surgeons Adult Cardiac Surgery DatabaseArtery bypass graft surgeryAdult Cardiac Surgery DatabasePost-CABG mortalityBypass graft surgeryCoronary artery bypassRetrospective cohort studyLow operative mortalityPercentage of patientsCardiac Surgery DatabaseClinical decision makingArtery bypassGraft surgeryValve surgeryCohort studyCABG proceduresPrimary outcomeSurgery Database
2019
Predictors of new persistent opioid use after coronary artery bypass grafting
Clement K, Canner J, Lawton J, Whitman G, Grant M, Sussman M. Predictors of new persistent opioid use after coronary artery bypass grafting. Journal Of Thoracic And Cardiovascular Surgery 2019, 160: 954-963.e4. PMID: 32007246, DOI: 10.1016/j.jtcvs.2019.09.137.Peer-Reviewed Original ResearchMeSH KeywordsAdministrative Claims, HealthcareAgedAmbulatory CareAnalgesics, OpioidCoronary Artery BypassDatabases, FactualDrug Administration ScheduleDrug PrescriptionsFemaleHumansMaleMiddle AgedOpioid-Related DisordersPain, PostoperativePractice Patterns, Physicians'Retrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeConceptsNew persistent opioid usePersistent opioid useCoronary artery bypassArtery bypassOpioid useOpioid prescriptionsPerioperative periodNaïve patientsChronic obstructive pulmonary diseaseAmount of opioidsAppropriate opioid prescribingObstructive pulmonary diseaseMultivariable logistic regressionPrescription opioid overdosePrior substance abuseInsurance claims dataOpioid requirementsOutpatient opioidsOpioid prescribingCardiac surgeryPulmonary diseaseOpioid dependenceProspective studyRisk factorsFemale genderDischarge Hemoglobin Level and 30-Day Readmission Rates After Coronary Artery Bypass Surgery
Cho B, DeMario V, Grant M, Hensley N, Brown C, Hebbar S, Mandal K, Whitman G, Frank S. Discharge Hemoglobin Level and 30-Day Readmission Rates After Coronary Artery Bypass Surgery. Anesthesia & Analgesia 2019, 128: 342-348. PMID: 30059402, PMCID: PMC6533067, DOI: 10.1213/ane.0000000000003671.Peer-Reviewed Original ResearchConceptsDischarge Hb levelsDischarge hemoglobin levelsReadmission ratesHb levelsPatient characteristicsHemoglobin levelsMultivariable analysisBlood utilizationCoronary artery bypass surgeryCertain patient comorbiditiesRestrictive transfusion strategyCharlson Comorbidity IndexCoronary artery bypassArtery bypass surgeryLarge randomized trialsRisk-adjusted oddsSimilar patient characteristicsLow Hb levelsCABG patientsDischarge HbPreoperative comorbiditiesArtery bypassComorbidity indexBypass surgeryPatient comorbidities
2017
Complications of CO2 insufflation during endoscopic vein harvesting
Suarez‐Pierre A, Terasaki Y, Magruder J, Kapoor A, Grant M, Lawton J. Complications of CO2 insufflation during endoscopic vein harvesting. Journal Of Cardiac Surgery 2017, 32: 783-789. PMID: 29169212, DOI: 10.1111/jocs.13249.Peer-Reviewed Original Research
2008
Is Aprotinin Safe to Use in a Cohort at Increased Risk for Thrombotic Events: Results From a Randomized, Prospective Trial in Off-Pump Coronary Artery Bypass
Grant M, Kon Z, Joshi A, Christenson E, Kallam S, Burris N, Gu J, Poston R. Is Aprotinin Safe to Use in a Cohort at Increased Risk for Thrombotic Events: Results From a Randomized, Prospective Trial in Off-Pump Coronary Artery Bypass. The Annals Of Thoracic Surgery 2008, 86: 815-822. PMID: 18721566, PMCID: PMC2649734, DOI: 10.1016/j.athoracsur.2008.04.047.Peer-Reviewed Original ResearchConceptsAcute kidney injuryCoronary artery bypassThrombotic eventsAprotinin levelsAprotinin useArtery bypassDay 3Off-pump coronary artery bypassMore acute kidney injuryPostoperative acute kidney injurySubsequent acute kidney injuryPump coronary artery bypassAcute graft failureAdverse thrombotic eventsWeight-based protocolPercentage of patientsGlomerular filtration rateFavorable safety profileMultiple randomized trialsPostoperative hypercoagulable stateEGFR declineCerebrovascular eventsKidney injuryLower eGFRPlacebo groupWarm ischemia provokes inflammation and regional hypercoagulability within the heart during off-pump coronary artery bypass: a possible target for serine protease inhibition
Kon Z, Brown E, Grant M, Ozeki T, Burris N, Collins M, Kwon M, Poston R. Warm ischemia provokes inflammation and regional hypercoagulability within the heart during off-pump coronary artery bypass: a possible target for serine protease inhibition. European Journal Of Cardio-Thoracic Surgery 2008, 33: 215-221. PMID: 18068996, PMCID: PMC2605708, DOI: 10.1016/j.ejcts.2007.11.008.Peer-Reviewed Original ResearchConceptsPump coronary artery bypassCoronary artery bypassTranscardiac gradientCoronary occlusionArtery bypassMyocardial ischemiaTNF-alphaCoronary sinus bloodEarly graft failureRegional myocardial ischemiaProthrombotic stateGraft failureProtamine administrationSinus bloodConsecutive patientsIschemic injuryMyocardial injuryIL-8Warm ischemiaPathophysiologic consequencesSeries of biomarkersCoagulation systemOPCABIschemiaInflammation
2007
Simultaneous hybrid coronary revascularization reduces postoperative morbidity compared with results from conventional off-pump coronary artery bypass
Kon Z, Brown E, Tran R, Joshi A, Reicher B, Grant M, Kallam S, Burris N, Connerney I, Zimrin D, Poston R. Simultaneous hybrid coronary revascularization reduces postoperative morbidity compared with results from conventional off-pump coronary artery bypass. Journal Of Thoracic And Cardiovascular Surgery 2007, 135: 367-375. PMID: 18242270, PMCID: PMC2962576, DOI: 10.1016/j.jtcvs.2007.09.025.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnalysis of VarianceCase-Control StudiesCohort StudiesCoronary AngiographyCoronary Artery Bypass, Off-PumpCoronary StenosisFemaleFollow-Up StudiesHumansInternal Mammary-Coronary Artery AnastomosisLength of StayLogistic ModelsMaleMiddle AgedPain, PostoperativePilot ProjectsPostoperative ComplicationsProbabilityRisk AssessmentSensitivity and SpecificitySeverity of Illness IndexTime FactorsTomography, X-Ray ComputedTreatment OutcomeVascular PatencyConceptsPump coronary artery bypassCoronary artery bypassTarget vessel patencyActivation of coagulationArtery bypassMyocardial injuryHybrid procedureOff-pump coronary artery bypassMultivessel coronary artery diseaseSimultaneous hybrid coronary revascularizationLeft internal thoracic arteryHybrid coronary revascularizationInternal thoracic arteryCoronary artery diseaseIntensive care unitBetter perioperative outcomesEnzyme-linked immunosorbentPromising preliminary findingsOverall total costTranscardiac gradientCoronary revascularizationPerioperative morbidityPerioperative outcomesPostoperative morbidityArtery disease