2006
Environmentally Responsive and Reversible Regulation of Epidermal Barrier Function by γδ T Cells
Girardi M, Lewis JM, Filler RB, Hayday AC, Tigelaar RE. Environmentally Responsive and Reversible Regulation of Epidermal Barrier Function by γδ T Cells. Journal Of Investigative Dermatology 2006, 126: 808-814. PMID: 16439970, DOI: 10.1038/sj.jid.5700120.Peer-Reviewed Original ResearchConceptsDendritic epidermal T cellsT cellsGammadelta T cell-deficient miceLimited T cell receptor diversityT cell-deficient miceBarrier functionTCRdelta-/- miceT-cell receptor diversityEpidermal T cellsT cell compartmentΓδ T cellsBarrier function defectsEpidermal barrier functionTransepidermal water lossPathogen-specific antigensCutaneous inflammationCutaneous neoplasiaDeficient miceGammadelta cellsFunction defectsCutaneous physiologyFetal thymocytesEpidermal barrierHydration statusReceptor diversity
2004
Cutaneous biology of gammadelta T cells.
Girardi M. Cutaneous biology of gammadelta T cells. Advances In Dermatology 2004, 20: 203-15. PMID: 15544201.Peer-Reviewed Original ResearchConceptsGammadelta T cellsT cellsInappropriate inflammatory responseNoninfectious skin diseasesMajor disease categoriesMost T cellsCutaneous inflammationLymph nodesCutaneous neoplasmsCutaneous tumorsCutaneous diseaseInflammatory responseReceptor subtypesSkin diseasesDisease categoriesEpidermal barrierCutaneous biologyInflammationLaboratory animalsNeoplastic transformationTCR variabilityDiseaseEpithelial tissuesCellsRecent studies