Treatment of toxic epidermal necrolysis and concurrent COVID-19-associated hyperinflammatory syndrome with systemic corticosteroids and etanercept
Choi R, Garritano J, Laird M, Johnston M, Tkachenko E, Damsky W, Little AJ, McNiff J, Girardi M, Nelson CA. Treatment of toxic epidermal necrolysis and concurrent COVID-19-associated hyperinflammatory syndrome with systemic corticosteroids and etanercept. JAAD Case Reports 2022, 29: 139-141. PMID: 36160836, PMCID: PMC9485430, DOI: 10.1016/j.jdcr.2022.09.009.Peer-Reviewed Case Reports and Technical NotesTopical formulation based on disease-specific nanoparticles for single-dose cure of psoriasis
Mai Y, Ouyang Y, Yu M, Qin Y, Girardi M, Saltzman WM, Cocco E, Zhao C, Yu L, Jia Y, Xiao L, Dou L, Deng W, Liu Y, Xie J, Deng Y. Topical formulation based on disease-specific nanoparticles for single-dose cure of psoriasis. Journal Of Controlled Release 2022, 349: 354-366. PMID: 35817278, DOI: 10.1016/j.jconrel.2022.07.006.Peer-Reviewed Original ResearchConceptsHealthy skinPsoriasis treatmentTopical formulationsPsoriatic skinCurrent psoriasis treatmentsFirst-line treatmentSingle-dose cureLocal drug concentrationModerate psoriasisLesional skinSingle doseDermal atrophyTherapeutic levelsTherapeutic efficacyCorticosteroidsDrug concentrationsPsoriasisBNPBasal cellsSkin retentionSkinLesionsBioadhesive nanoparticlesTreatmentStratum corneum