2015
Quantifying hyperoxia-mediated damage to mammalian respiratory cilia-driven fluid flow using particle tracking velocimetry optical coherence tomography
Gamm UA, Huang BK, Syed M, Zhang X, Bhandari V, Choma MA. Quantifying hyperoxia-mediated damage to mammalian respiratory cilia-driven fluid flow using particle tracking velocimetry optical coherence tomography. Journal Of Biomedical Optics 2015, 20: 080505-080505. PMID: 26308164, PMCID: PMC4874052, DOI: 10.1117/1.jbo.20.8.080505.Peer-Reviewed Original ResearchConceptsOptical coherence tomographyMouse tracheaCoherence tomographyDrug-mediated modulationIntensive care unitRisk-benefit profileRespiratory failureCare unitOxygen supplementationRespiratory mucosaRespiratory epitheliumIndispensable treatmentImpaired capacityClinical useHyperoxiaTracheaFlow quantificationTomographyTreatmentDamagePatientsMucosaSupplementationEpithelium
2014
Resolving directional ambiguity in dynamic light scattering-based transverse motion velocimetry in optical coherence tomography.
Huang BK, Choma MA. Resolving directional ambiguity in dynamic light scattering-based transverse motion velocimetry in optical coherence tomography. Optics Letters 2014, 39: 521-4. PMID: 24487855, PMCID: PMC4174353, DOI: 10.1364/ol.39.000521.Peer-Reviewed Original ResearchConceptsTotal transverseDirectional velocityFunction calibrationTomography approachDirectional ambiguityScan axisDirectional velocity componentsThree-component velocimetryOptical coherence tomographyTransverse planeVelocity componentsLongitudinal angleCoherence tomographyDoppler velocimetryVelocimetryTransversePlane
2005
Spectral-domain phase microscopy.
Choma MA, Ellerbee AK, Yang C, Creazzo TL, Izatt JA. Spectral-domain phase microscopy. Optics Letters 2005, 30: 1162-4. PMID: 15945141, DOI: 10.1364/ol.30.001162.Peer-Reviewed Original ResearchConceptsSpectral domain phase microscopyShot-noise limitPhase-sensitive techniqueNanometer-scale motionCoherence gatingBroadband interferometryDisplacement sensitivityPhase microscopyPhase informationOptical coherence tomographyCoherence tomographyFunctional extensionAttractive techniqueInterferometryLiving cellsCellular motionMotionCellular dynamicsMicroscopyMeasurementsTechniqueGating