Timing of the onset of a developmental cell death is controlled by transcriptional induction of the C. elegans ced-3 caspase-encoding gene
Maurer CW, Chiorazzi M, Shaham S. Timing of the onset of a developmental cell death is controlled by transcriptional induction of the C. elegans ced-3 caspase-encoding gene. Development 2007, 134: 1357-1368. PMID: 17329362, DOI: 10.1242/dev.02818.Peer-Reviewed Original ResearchConceptsCED-3 caspaseCell deathEGL-1Animal developmentTranscriptional inductionCed-9/BclCED-4/ApafTemporal controlPAL-1Such temporal regulationC. elegans homologCell death onsetDevelopmental expression patternsDevelopmental cell deathCell-specific deathEgl-1 expressionCED-4CED-3CED-9Transcriptional regulationSomatic cellsTemporal regulationPromoter sitesExpression patternsTranscription