2001
Results of a Pilot Trial Comparing Prolonged Intravenous Antibiotics With Sequential Intravenous/Oral Antibiotics for Children With Perforated Appendicitis
Rice H, Brown R, Gollin G, Caty M, Gilbert J, Skinner M, Glick P, Azizkhan R. Results of a Pilot Trial Comparing Prolonged Intravenous Antibiotics With Sequential Intravenous/Oral Antibiotics for Children With Perforated Appendicitis. JAMA Surgery 2001, 136: 1391-1395. PMID: 11735866, DOI: 10.1001/archsurg.136.12.1391.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAdolescentAmpicillinAppendicitisChildChild, PreschoolClavulanic AcidClindamycinDrug Administration ScheduleDrug Therapy, CombinationFemaleGentamicinsHumansInjections, IntravenousIntestinal PerforationMaleMetronidazolePilot ProjectsProspective StudiesRupture, SpontaneousConceptsNormal white blood cell countWhite blood cell countDuration of feverBlood cell countTreatment equivalenceIntravenous antibioticsOral antibioticsOral intakeOutcome measuresCell countShort courseProlonged intravenous antibioticsOral antibiotic therapyTertiary children's hospitalSecondary outcome measuresPrimary outcome measurePerforated appendicitisAntibiotic therapyChildren's HospitalMulticenter studyTherapy resultsClinical trialsPilot trialPatient chargesAppendicitis
1999
Does early ultrasonography affect management of pediatric appendicitis? A prospective analysis
Rice H, Arbesman M, Martin D, Brown R, Gollin G, Gilbert J, Caty M, Glick P, Azizkhan R. Does early ultrasonography affect management of pediatric appendicitis? A prospective analysis. Journal Of Pediatric Surgery 1999, 34: 754-759. PMID: 10359177, DOI: 10.1016/s0022-3468(99)90369-x.Peer-Reviewed Original ResearchConceptsEarly ultrasonographyClinical utilityEquivocal findingsHigh clinical suspicionHospital resource utilizationRisk of appendicitisDiagnosis of appendicitisInitial management planPediatric surgery fellowsProper clinical roleSubstantial clinical utilityClinical suspicionPediatric appendicitisInitial presentationPossible appendicitisStudy cohortClinical managementDifficult diagnosisAppendicitisClinical roleProspective analysisClinical judgmentPatient carePatientsUltrasonography