1995
Ancylostoma caninum anticoagulant peptide: a hookworm-derived inhibitor of human coagulation factor Xa.
Cappello M, Vlasuk G, Bergum P, Huang S, Hotez P. Ancylostoma caninum anticoagulant peptide: a hookworm-derived inhibitor of human coagulation factor Xa. Proceedings Of The National Academy Of Sciences Of The United States Of America 1995, 92: 6152-6156. PMID: 7597095, PMCID: PMC41660, DOI: 10.1073/pnas.92.13.6152.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAncylostomaAnimalsArthropod ProteinsBlood CoagulationChromatography, GelChromatography, High Pressure LiquidChromatography, Ion ExchangeFactor Xa InhibitorsHelminth ProteinsHirudinsHumansIntercellular Signaling Peptides and ProteinsKineticsMass SpectrometryMolecular Sequence DataPeptide FragmentsPeptidesProthrombin TimeRecombinant ProteinsSerine Proteinase InhibitorsTicksConceptsBlood lossFactor XaIntestinal blood lossGastrointestinal blood lossHuman hookworm infectionIron deficiency anemiaSoil-transmitted helminthsHuman coagulation factor XaFree factor XaAnticoagulant peptideSpecific inhibitorHookworm infectionDeficiency anemiaProthrombin timeIntestinal mucosaCoagulation factor XaMajor causeRecombinant hirudinChromogenic assayMajor anticoagulantAdult wormsAnticoagulantsProtease inhibitorsHuman coagulationInhibitors
1994
Hyaluronidases Of The Gastrointestinal Invasive Nematodes Ancylostoma Caninum And Anisakis Simplex: Possible Functions In The Pathogenesis Of Human Zoonoses
Hotez P, Cappello M, Hawdon J, Beckers C, Sakanari J. Hyaluronidases Of The Gastrointestinal Invasive Nematodes Ancylostoma Caninum And Anisakis Simplex: Possible Functions In The Pathogenesis Of Human Zoonoses. The Journal Of Infectious Diseases 1994, 170: 918-926. PMID: 7930737, DOI: 10.1093/infdis/170.4.918.Peer-Reviewed Original Research