Ancylostoma ceylanicum anticoagulant peptide-1: role of the predicted reactive site amino acid in mediating inhibition of coagulation factors Xa and VIIa
Mieszczanek J, Harrison LM, Cappello M. Ancylostoma ceylanicum anticoagulant peptide-1: role of the predicted reactive site amino acid in mediating inhibition of coagulation factors Xa and VIIa. Molecular And Biochemical Parasitology 2004, 137: 151-159. PMID: 15279961, DOI: 10.1016/j.molbiopara.2004.05.011.Peer-Reviewed Original ResearchConceptsCoagulation factor XaAmino acid sequence similarityFactor XaGastrointestinal blood lossIron deficiency anemiaSite amino acid residuesAmino acid residuesSite amino acidsMechanism of actionBlood lossHookworm infectionSequence similarityDeficiency anemiaLeading causeFactor VIIa/tissue factor complexFactor complexCoagulation inhibitorsPeptide-1Ancylostoma caninum anticoagulant peptide 5Coagulation responseAcid residuesNon-active siteA. ceylanicumAnticoagulantsTissue factor complex