2014
Molecular cloning and characterization of a nematode polyprotein antigen/allergen from the human and animal hookworm Ancylostoma ceylanicum
Fairfax KC, Harrison LM, Cappello M. Molecular cloning and characterization of a nematode polyprotein antigen/allergen from the human and animal hookworm Ancylostoma ceylanicum. Molecular And Biochemical Parasitology 2014, 198: 37-44. PMID: 25481749, PMCID: PMC4354846, DOI: 10.1016/j.molbiopara.2014.11.005.Peer-Reviewed Original ResearchConceptsAmino acid sequenceFatty acids de novoShares sequence identityExcretory/secretory proteinsPseudocoelomic spaceMolecular cloningCis-parinaric acidPartial cDNASequence identityAcid sequenceFatty acidsSimilar proteinsSecretory proteinsHookworm biologyRecombinant subunitsSoluble adult worm extractProteinAntigens/allergensSubunits
2011
Twenty-First Century Progress Toward the Global Control of Human Hookworm Infection
Bungiro R, Cappello M. Twenty-First Century Progress Toward the Global Control of Human Hookworm Infection. Current Infectious Disease Reports 2011, 13: 210. PMID: 21462001, DOI: 10.1007/s11908-011-0182-z.Peer-Reviewed Original ResearchHuman hookworm infectionHost immune responseCandidate vaccine antigensHigher infection rateExcretory/secretory proteinsImmunoepidemiological studiesTreatment failureHookworm infectionMass chemotherapyImmune responseAnimal modelsParasitic infectionsVaccine antigensMolecular pathogenesisInfection rateHookworm diseaseReduced efficacyProtease inhibitorsHookwormInfectionSaharan AfricaRecent studiesContinued useSecretory proteinsAsthma