Featured Publications
Comparison of percutaneous vs oral infection of hamsters with the hookworm Ancylostoma ceylanicum: Parasite development, pathology and primary immune response
Bungiro RD, Harrison LM, Dondji B, Cappello M. Comparison of percutaneous vs oral infection of hamsters with the hookworm Ancylostoma ceylanicum: Parasite development, pathology and primary immune response. PLOS Neglected Tropical Diseases 2022, 16: e0010098. PMID: 34986139, PMCID: PMC8765627, DOI: 10.1371/journal.pntd.0010098.Peer-Reviewed Original ResearchConceptsCellular immune responsesGolden Syrian hamstersImmune responsePercutaneous infectionOral infectionSyrian hamstersAncylostoma ceylanicumPrimary immune responseRoute of infectionModerate growth delayFaecal egg outputPercutaneous groupImmunological manifestationsAntibody titersHookworm Ancylostoma ceylanicumInfected hamstersWorm recoveryLarval antigensBlood hemoglobinDisease pathogenesisHost responseGrowth delayHuman infectionsInfectionA. ceylanicum
1996
Molecular Approaches to Vaccinating against Hookworm Disease
Hotez P, Hawdon J, Cappello M, Jones B, Ghosh K, Volvovitz F, Shu-Hua X. Molecular Approaches to Vaccinating against Hookworm Disease. Pediatric Research 1996, 40: 515-521. PMID: 8888276, DOI: 10.1203/00006450-199610000-00001.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsLarval antigensVaccine antigensInfective hookworm larvaeProtective immunityHookworm infectionAdjuvant formulationsDrug chemotherapyAlternative vaccinesVaccine routeLive vaccineGenetic immunizationVaccine developmentHookworm larvaeHookworm diseaseParasitic diseasesAntigenPhase IVaccineAncylostoma caninumProtein 1ImmunizationTarget populationAcceptable approachDiseaseASP-2