2011
Ancylostoma ceylanicum Excretory–Secretory Protein 2 Adopts a Netrin-Like Fold and Defines a Novel Family of Nematode Proteins
Kucera K, Harrison LM, Cappello M, Modis Y. Ancylostoma ceylanicum Excretory–Secretory Protein 2 Adopts a Netrin-Like Fold and Defines a Novel Family of Nematode Proteins. Journal Of Molecular Biology 2011, 408: 9-17. PMID: 21352830, PMCID: PMC3070796, DOI: 10.1016/j.jmb.2011.02.033.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAncylostomaAncylostomatoideaAncylostomiasisAnimalsComplement System ProteinsHelminth ProteinsHumansMatrix MetalloproteinasesMolecular Sequence DataNerve Growth FactorsNetrin-1Protein ConformationProtein FoldingSequence Homology, Amino AcidTissue Inhibitor of MetalloproteinasesTumor Suppressor ProteinsConceptsMatrix metalloproteasesHost immune responseComplement factor C3Nematode proteinsProtein 2Complement-mediated cell lysisHookworm anaemiaMucosal vaccinesImmune responseUseful model organismFactor C3Decoy receptorDisease pathogenesisTissue inhibitorIntestinal attachmentNovel familyAncylostoma ceylanicumImmunoreactive moleculesAdult wormsGlobal healthModel organismsHookwormSequence homologyÅ resolutionHuman parasites
2004
Hookworm infection: new developments and prospects for control
Bungiro R, Cappello M. Hookworm infection: new developments and prospects for control. Current Opinion In Infectious Diseases 2004, 17: 421-426. PMID: 15353961, DOI: 10.1097/00001432-200410000-00006.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHookworm infectionHookworm diseaseEffective global controlPathological immune responsesMajor health burdenParasite virulence factorsNew chemotherapeutic agentsDevelopment of vaccinesHookworm anaemiaImmunoepidemiological studiesMass chemotherapyHealth burdenImmune responseMolecular pathogenesisGrowth delayChemotherapeutic agentsInfectionVaccineSocioeconomic statusDiseaseVirulence factorsGlobal healthBenzimidazole anthelminthicsPathogenesisAnthelminthic resistance