A furoxan – amodiaquine hybrid as a potential therapeutic for three parasitic diseases
Mott BT, Cheng KC, Guha R, Kommer VP, Williams DL, Vermeire JJ, Cappello M, Maloney DJ, Rai G, Jadhav A, Simeonov A, Inglese J, Posner GH, Thomas CJ. A furoxan – amodiaquine hybrid as a potential therapeutic for three parasitic diseases. RSC Medicinal Chemistry 2012, 3: 1505-1511. PMID: 23205265, PMCID: PMC3509744, DOI: 10.1039/c2md20238g.Peer-Reviewed Original ResearchParasitic diseasesEx vivo assaysAntimalarial drug amodiaquineNovel therapiesEffective treatmentParasite Plasmodium falciparumSchistosoma mansoniAncylostoma ceylanicumParasitic targetsPotential therapeuticsMultiple mechanismsVivo assaysDiseaseFrequent emergenceAmodiaquineTherapyHuman populationMansoniFalciparum