2008
Orthologs of macrophage migration inhibitory factor from parasitic nematodes
Vermeire JJ, Cho Y, Lolis E, Bucala R, Cappello M. Orthologs of macrophage migration inhibitory factor from parasitic nematodes. Trends In Parasitology 2008, 24: 355-363. PMID: 18603473, PMCID: PMC3615561, DOI: 10.1016/j.pt.2008.04.007.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsMacrophage migration inhibitory factorParasitic nematodesMigration inhibitory factorHost-parasite interfaceSpecies-specific activityDevelopmental biologyThree-dimensional structureMammalian hostsInhibitory factorHost cellular immune responseParasite survivalChronic helminth infectionsVaccine-based strategiesCellular immune responsesOrthologsMIF moleculeParasite moleculesNematodesHost cytokinesImmune responseHelminth infectionsDisease controlIdeal targetRecent progressMolecules
2004
Hookworm infection: molecular mechanisms of disease and targets for control
Jones B, Cappello M. Hookworm infection: molecular mechanisms of disease and targets for control. Drug Discovery Today Disease Mechanisms 2004, 1: 217-222. DOI: 10.1016/j.ddmec.2004.10.004.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsHookworm anaemiaSmall intestineMajor global health problemStage of diseaseGlobal health problemProtein-energy malnutritionVirulence factorsMolecular mechanismsPregnant womenSevere anemiaVaccine strategiesPlatelet inhibitorsPancreatic digestive enzymesHealth burdenEnergy malnutritionHost small intestineHealth problemsGrowth delayAnemiaHookworm diseaseIntestinal nematodesDisease controlChild mortalityMount Sinai SchoolPotential target