The role of genetics on behavioral outcomes in nonsyndromic sagittal synostosis.
Alper D, Almeida M, Hu K, Yang J, Timberlake A, Shah J, Persing J, Alperovich M. The role of genetics on behavioral outcomes in nonsyndromic sagittal synostosis. Journal Of Neurosurgery Pediatrics 2024, 34: 234-245. PMID: 38875721, DOI: 10.3171/2024.4.peds23510.Peer-Reviewed Original ResearchBehavioral outcomesNonsyndromic sagittal synostosisSocial Responsiveness Scale-2nd editionBehavior Rating InventoryAttention-deficit/hyperactivity disorderSagittal synostosisPly geneRelative to controlsExecutive functionAttention-deficit/hyperactivityExternalizing behaviorsExternalizing problemsLoss of functionBehavior problemsASD domainAssociated with worse scoresOutcomes of patientsRule-breakingParents of children aged 6Treating sagittal synostosisOlder ageAssociation of mutationsBehavior scoresSociodemographic factorsPly groupsComparison of emotional and behavioral regulation between metopic and sagittal synostosis
Almeida M, Alper D, Parikh N, De Baun H, Kammien A, Persing J, Alperovich M. Comparison of emotional and behavioral regulation between metopic and sagittal synostosis. Child's Nervous System 2024, 40: 2789-2799. PMID: 38691155, DOI: 10.1007/s00381-024-06387-8.Peer-Reviewed Original ResearchIntelligence quotientBehavior Rating Inventory of Executive Function-2Wechsler Abbreviated Scale of IntelligenceSocial Responsiveness Scale-2Behavior Rating InventoryWechsler Abbreviated ScaleExecutive function subscalesChild Behavior ChecklistExecutive function scoresScale of IntelligenceWASI-IIBRIEF-2Conners-3Executive functionExternalizing behaviorsBehavior ChecklistBehavioral regulationProblems subscaleSchool ageBehavioral assessmentBehavioral difficultiesScale-2Behavioral outcomesRule-breakingBehavioral differences