2016
Whole genomic characterization of Korean porcine G8P[7] reassortant rotaviruses
Park J, Park S, Woo N, Kim D, Seo J, Alfajaro M, Kim J, Soliman M, Baek Y, Cho E, Kwon J, Choi J, Kang M, Matthijnssens J, Cho K. Whole genomic characterization of Korean porcine G8P[7] reassortant rotaviruses. Archives Of Virology 2016, 161: 2835-2841. PMID: 27393603, DOI: 10.1007/s00705-016-2945-1.Peer-Reviewed Original Research
2015
Genetic diversity of the VP7, VP4 and VP6 genes of Korean porcine group C rotaviruses
Jeong Y, Matthijnssens J, Kim D, Kim J, Alfajaro M, Park J, Hosmillo M, Son K, Soliman M, Baek Y, Kwon J, Choi J, Kang M, Cho K. Genetic diversity of the VP7, VP4 and VP6 genes of Korean porcine group C rotaviruses. Veterinary Microbiology 2015, 176: 61-69. PMID: 25592760, DOI: 10.1016/j.vetmic.2014.12.024.Peer-Reviewed Original ResearchConceptsGenetic diversityPorcine group C rotavirusPorcine RVCRVC strainsLarge genetic diversityVP6 geneGroup C rotavirusFrequent reassortment eventsStrong geographical differencesPhylogenetic dataPhylogenetic analysisHost speciesHuman RVCORF sequencesC rotavirusReassortment eventsGene segmentsPig industryG7 genotypeImportant pathogenGenesDiversityEconomic impactVP4 sequencesDefinitive cut
2014
Comparison of pathogenicities and nucleotide changes between porcine and bovine reassortant rotavirus strains possessing the same genotype constellation in piglets and calves
Park J, Kim D, Matthijnssens J, Kwon H, Zeller M, Alfajaro M, Son K, Hosmillo M, Ryu E, Kim J, Lee J, Park S, Kang M, Kwon J, Choi J, Cho K. Comparison of pathogenicities and nucleotide changes between porcine and bovine reassortant rotavirus strains possessing the same genotype constellation in piglets and calves. Veterinary Microbiology 2014, 172: 51-62. PMID: 24861840, DOI: 10.1016/j.vetmic.2014.04.010.Peer-Reviewed Original ResearchConceptsHost range restrictionGenotype constellationHistopathological changesCritical molecular determinantsSmall intestineReassortant rotavirusesComparison of pathogenicityDiarrheic pigletsPathological phenotypesDifferent virulenceReassortant strainsPigletsCalvesNSP4 genesSpecific mutationsAmino acid substitutionsRotavirus evolutionMolecular determinantsNSP3 genePathogenicityVirulenceAcid substitutionsNucleotide changesDiarrheaRotavirus
2013
Molecular epidemiology of Korean porcine sapeloviruses
Son K, Kim D, Matthijnssens J, Kwon H, Park J, Hosmillo M, Alfajaro M, Ryu E, Kim J, Kang M, Cho K. Molecular epidemiology of Korean porcine sapeloviruses. Archives Of Virology 2013, 159: 1175-1180. PMID: 24232913, PMCID: PMC7087272, DOI: 10.1007/s00705-013-1901-6.Peer-Reviewed Original ResearchConceptsGenetic diversityPorcine sapelovirusPronounced genetic diversityVP1 geneDiarrhea fecal samplesPhylogenetic analysisPrimer pairsPSV infectionGenesPCR assaysDiversityRT-PCRKorean pigsSapelovirusFecal samplesMolecular epidemiologyDiarrhea samplesBacteriaInfectionEnteric virusesHigher proportionAssaysPigsStrainsDifferent virulence of porcine and porcine-like bovine rotavirus strains with genetically nearly identical genomes in piglets and calves
Park J, Kim H, Matthijnssens J, Alfajaro M, Kim D, Son K, Kwon H, Hosmillo M, Ryu E, Kim J, Cena R, Lee J, Kang M, Park S, Cho K. Different virulence of porcine and porcine-like bovine rotavirus strains with genetically nearly identical genomes in piglets and calves. Veterinary Research 2013, 44: 88. PMID: 24083947, PMCID: PMC3851489, DOI: 10.1186/1297-9716-44-88.Peer-Reviewed Original ResearchConceptsHistopathological changesSmall intestineGroup A rotavirusesDirect interspecies transmissionGenotype constellationCritical molecular determinantsFull-length sequencing analysisA rotavirusesBovine rotavirusVP1-VP4Pathological phenotypesDifferent virulencePigletsDiarrheaInterspecies transmissionAmino acid mutationsRotavirusCalvesIntestineSpecific mutationsTropismMolecular determinantsSequencing analysisUntranslated regionPorcine
2011
Reassortment among bovine, porcine and human rotavirus strains results in G8P[7] and G6P[7] strains isolated from cattle in South Korea
Park S, Matthijnssens J, Saif L, Kim H, Park J, Alfajaro M, Kim D, Son K, Yang D, Hyun B, Kang M, Cho K. Reassortment among bovine, porcine and human rotavirus strains results in G8P[7] and G6P[7] strains isolated from cattle in South Korea. Veterinary Microbiology 2011, 152: 55-66. PMID: 21592683, DOI: 10.1016/j.vetmic.2011.04.015.Peer-Reviewed Original ResearchConceptsGenotype constellationT1-E1-H1 genotypesH1 genotype constellationFull-length ORFDetailed phylogenetic analysisGroup A rotavirusesC1-M2Phylogenetic analysisComplete genomeN2-T6Genome constellationM2-A3VP1-4I5-R1Bovine group A rotavirusesHeterologous speciesI2-R2A1-N1ReassortmentG8 genotypeSingle strainReassortant strainsGenotypesStrainsGenome
2010
Molecular detection of genotype 3 porcine hepatitis E virus in aborted fetuses and their sows
Hosmillo M, Jeong Y, Kim H, Park J, Nayak M, Alfajaro M, Collantes T, Park S, Ikuta K, Yunoki M, Kang M, Park S, Cho K. Molecular detection of genotype 3 porcine hepatitis E virus in aborted fetuses and their sows. Archives Of Virology 2010, 155: 1157-1161. PMID: 20458510, DOI: 10.1007/s00705-010-0679-z.Peer-Reviewed Original ResearchConceptsPorcine circovirus type 2Polymerase chain reactionHepatitis E virus RNAGenotype 3 HEVHEV-positive samplesHepatitis E virusReal-time RT-PCRViral copies/HEV infectionHEV RNATransplacental infectionCircovirus type 2E virusCopies/Type 2PCV2 coinfectionSerum samplesFetusesRT-PCRVirus RNAChain reactionReproductive failureInfectionReverse transcriptionMolecular detection