Anti-rotavirus effects by combination therapy of stevioside and Sophora flavescens extract
Alfajaro M, Rho M, Kim H, Park J, Kim D, Hosmillo M, Son K, Lee J, Park S, Kang M, Ryu Y, Park K, Oh H, Lee S, Park S, Lee W, Cho K. Anti-rotavirus effects by combination therapy of stevioside and Sophora flavescens extract. Research In Veterinary Science 2014, 96: 567-575. PMID: 24704033, DOI: 10.1016/j.rvsc.2014.03.011.Peer-Reviewed Original ResearchConceptsCombination therapyAnti-rotaviral activityAnti-rotavirus effectIntestinal lesion scoresLethal dose 50Rotavirus enteritisCurative medicationsRotaviral enteritisSophora flavescensRotaviral diarrheaOrgan weightsPiglet modelPathological changesFecal virusBody weightTherapyVirus replicationLesion scoresSingle treatmentDose 50Porcine rotavirusAdverse effectsPreliminary dataDiarrheaEnteritis