2016
Pathogenesis of Korean SapelovirusA in piglets and chicks
Kim D, Kang M, Son K, Bak G, Park J, Hosmillo M, Seo J, Kim J, Alfajaro M, Soliman M, Baek Y, Cho E, Lee J, Kwon J, Choi J, Goodfellow I, Cho K. Pathogenesis of Korean SapelovirusA in piglets and chicks. Journal Of General Virology 2016, 97: 2566-2574. PMID: 27487773, PMCID: PMC5078829, DOI: 10.1099/jgv.0.000571.Peer-Reviewed Original ResearchConceptsExtra-intestinal organsHigher viral RNA levelsNon-suppurative myelitisViral RNA levelsReal-time reverse transcription PCRCells of pigsIntestinal pathologyReverse transcription-PCRViral antigensViral pathogenesisReproductive disordersSapelovirus APathogenesisPorcine sapelovirusVirus entryCultured cell linesRNA levelsEpithelial cellsTranscription-PCRFecal samplesPigletsPneumoniaCell linesSialic acidPathology
2012
Pathogenicity characterization of a bovine triple reassortant rotavirus in calves and piglets
Kim H, Park J, Alfajaro M, Kim D, Hosmillo M, Son K, Lee J, Bae Y, Park S, Kang M, Cho K. Pathogenicity characterization of a bovine triple reassortant rotavirus in calves and piglets. Veterinary Microbiology 2012, 159: 11-22. PMID: 22465801, DOI: 10.1016/j.vetmic.2012.03.017.Peer-Reviewed Original ResearchConceptsExtra-intestinal organsMesenteric lymph nodesCross-species pathogenicityReassortant rotavirusesLymph nodesIntestinal pathologyPersistent severe diarrheaSevere intestinal pathologyExtra-intestinal infectionsDiarrhea fecal samplesReal-time RT-PCRGreen real-time RT-PCRSYBR Green real-time RT-PCRSevere diarrheaCerebrospinal fluidChoroid plexusViral replicationRotavirusRT-PCRViral RNAFecal samplesPigletsDiarrheaPublic healthPathology
2011
Intestinal and extra-intestinal pathogenicity of a bovine reassortant rotavirus in calves and piglets
Kim H, Park J, Matthijnssens J, Lee J, Bae Y, Alfajaro M, Park S, Kang M, Cho K. Intestinal and extra-intestinal pathogenicity of a bovine reassortant rotavirus in calves and piglets. Veterinary Microbiology 2011, 152: 291-303. PMID: 21658866, DOI: 10.1016/j.vetmic.2011.05.017.Peer-Reviewed Original ResearchConceptsGroup A rotavirusesExtra-intestinal spreadCross-species pathogenicityPost-inoculation day 1Intestinal villous atrophyVirus-inoculated calvesExtra-intestinal organsMesenteric lymph nodesBovine group A rotavirusesColostrum-deprived calvesViral RNAReal-time RT-PCRNSP4 gene segmentsGreen real-time RT-PCRSYBR Green real-time RT-PCRVillous atrophyLymph nodesClinical symptomsGene segmentsSevere diarrheaCerebrospinal fluidChoroid plexusDay 1Viral replicationReassortant rotaviruses