2024
Promoting Collaborative Scholarship During the COVID-19 Pandemic Through an Innovative COVID-19 Data Explorer and Repository at Yale School of Medicine: Development and Usability Study
Victoria-Castro A, Arora T, Simonov M, Biswas A, Alausa J, Subair L, Gerber B, Nguyen A, Hsiao A, Hintz R, Yamamoto Y, Soufer R, Desir G, Wilson F, Villanueva M. Promoting Collaborative Scholarship During the COVID-19 Pandemic Through an Innovative COVID-19 Data Explorer and Repository at Yale School of Medicine: Development and Usability Study. JMIR Formative Research 2024, 8: e52120. PMID: 39226547, PMCID: PMC11408881, DOI: 10.2196/52120.Peer-Reviewed Original ResearchUsing Data-To-Care Strategies to Optimize the HIV Care Continuum in Connecticut: Results From a Randomized Controlled Trial
Machavariani E, Miceli J, Altice F, Fanfair R, Speers S, Nichols L, Jenkins H, Villanueva M. Using Data-To-Care Strategies to Optimize the HIV Care Continuum in Connecticut: Results From a Randomized Controlled Trial. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2024, 96: 40-50. PMID: 38324241, PMCID: PMC11009056, DOI: 10.1097/qai.0000000000003391.Peer-Reviewed Original ResearchDisease intervention specialistsCare continuum outcomesHIV care continuum outcomesHIV care continuumRandomized controlled trialsHIV risk categoryCare continuumStandard-of-careData-to-CareViral suppressionRe-engagementPredictor of re-engagementRisk categoriesHIV careRe-engage peopleMultivariate regression modelHIV clinicPredictors of retentionDetectable HIV-1 RNAIntervention specialistsControlled trialsPredictors of VSPre-randomizationCareHIV-1 RNALemierre syndrome with pulmonary empyema caused by Prevotella intermedia
Simsek B, Zhang R, Morton C, Villanueva M. Lemierre syndrome with pulmonary empyema caused by Prevotella intermedia. BMJ Case Reports 2024, 17: e258158. PMID: 38490705, PMCID: PMC10946344, DOI: 10.1136/bcr-2023-258158.Peer-Reviewed Original ResearchConceptsLemierre's syndromeMultiple cavitary lung lesionsCavitary lung lesionsChest tube placementLoculated pleural effusionPrevotella intermediaAntimicrobial therapyRare causePleural effusionPulmonary empyemaTube placementRare diseaseLung lesionsHealthy menSyndromeLemierreEmpyemaAbscessEffusionTherapyLesions
2023
Using the exploration, preparation, implementation, sustainment (EPIS) framework to assess the cooperative re-engagement controlled trial (CoRECT)
Elder H, Lang S, Villanueva M, John B, Roosevelt K, Altice F, Brady K, Gibson B, Buchelli M, DeMaria A, Randall L. Using the exploration, preparation, implementation, sustainment (EPIS) framework to assess the cooperative re-engagement controlled trial (CoRECT). Frontiers In Public Health 2023, 11: 1223149. PMID: 38106893, PMCID: PMC10722986, DOI: 10.3389/fpubh.2023.1223149.Peer-Reviewed Original ResearchConceptsPublic health surveillance dataHealth surveillance dataHIV careSurveillance dataHealth department jurisdictionsPublic health practicePublic health agenciesStudy protocolClinic dataClinic partnersCase identificationHealth practicesHealth agenciesIntervention design processTrial sitesIntervention developmentTrialsCareInterventionSustainment (EPIS) frameworkEPIS frameworkIterative discussionsStaff capacityCommunity partnersRe-Engagement1483. Real-time Creation of HCV Treatment Cascades in Clinics to Improve HCV Treatment Rates Among Patients with HIV/HCV Co-infection
Wegener M, Brooks R, Nichols L, Villanueva M. 1483. Real-time Creation of HCV Treatment Cascades in Clinics to Improve HCV Treatment Rates Among Patients with HIV/HCV Co-infection. Open Forum Infectious Diseases 2023, 10: ofad500.1319. PMCID: PMC10677588, DOI: 10.1093/ofid/ofad500.1319.Peer-Reviewed Original ResearchHIV/HCVHCV treatmentHealth departmentsHIV/HCV Co-infectionSurveillance dataHCV Co-InfectionHCV PCR testingHCV surveillance dataHCV treatment cascadeHCV treatment ratesClinical care dataCounty Health DepartmentHCV careRyan WhiteSVR ratesHCV diagnosisTreatment cascadeTreatment initiationCo-InfectionHCV surveillanceTreatment eligibilityViral clearanceClinic levelCase conferencingMedical records2510. Adapting the CDC HCV viral clearance cascade methodology for persons with HIV (PWH) and HCV co-infection in 5 Health Department Jurisdictions in the US
Wegener M, Brooks R, Nichols L, Villanueva M. 2510. Adapting the CDC HCV viral clearance cascade methodology for persons with HIV (PWH) and HCV co-infection in 5 Health Department Jurisdictions in the US. Open Forum Infectious Diseases 2023, 10: ofad500.2128. PMCID: PMC10678948, DOI: 10.1093/ofid/ofad500.2128.Peer-Reviewed Original ResearchHCV surveillance dataPrevalent HIVRecent HCVViral clearanceViral testingHealth jurisdictionsInitial infectionHIV transmission risk factorsHIV/HCV coinfectionUndetectable HIV viral loadSurveillance dataHCV cure ratesHCV test resultsHCV viral clearanceHealth department jurisdictionsHIV viral loadHIV/HCVCo-infected populationTransmission risk factorsCoinfected populationHCV cascadeHCV coinfectionHCV microeliminationHCV clearanceHIV carePrevalence and Correlates of Physical Inactivity Among Individuals with HIV During the First COVID-19 Wave: A Cross-sectional Survey
Harsono D, Deng Y, Chung S, Barakat L, Friedland G, Villanueva M, Yager J, Justen M, Edelman E. Prevalence and Correlates of Physical Inactivity Among Individuals with HIV During the First COVID-19 Wave: A Cross-sectional Survey. AIDS And Behavior 2023, 28: 1531-1545. PMID: 37824037, PMCID: PMC11349050, DOI: 10.1007/s10461-023-04170-5.Peer-Reviewed Original ResearchPhysical activity guidelinesPhysical inactivityPhysical activityDetectable HIV viral loadSelf-reported physical activitySample of PWHHIV viral loadPhysical activity levelsUnhealthy alcohol useFirst COVID-19 waveImproved health outcomesCross-sectional surveyHIV clinicCOVID-19 waveActivity guidelinesAdjusted analysisCOVID-19 transmissionViral loadTobacco useCoping strategiesSedentary lifestyleLower oddsPsychological coping strategiesHealth outcomesDisease controlImproving HIV and HCV Testing in Substance Use Disorder Programs (SUDs) That Provide Medications for Opiate Use Disorder (MOUD): Role of Addressing Barriers and Implementing Universal and Site-Specific Approaches
Brooks R, Wegener M, Freeman B, Fowles C, Madden L, Tetrault J, Nichols L, Altice F, Villanueva M. Improving HIV and HCV Testing in Substance Use Disorder Programs (SUDs) That Provide Medications for Opiate Use Disorder (MOUD): Role of Addressing Barriers and Implementing Universal and Site-Specific Approaches. Health Promotion Practice 2023, 24: 1018-1028. PMID: 37439759, DOI: 10.1177/15248399231169791.Peer-Reviewed Original ResearchConceptsHIV/HCV coinfectionSubstance use disorder programsHCV testingOpiate use disorderHCV coinfectionUse disordersNominal group techniqueSubstance use disorder treatment centersCascade of careRates of HIVDisorder treatment centersQuality improvement effortsRate of testingHCV acquisitionHCV cureImproving HIVSUD clinicsHepatitis CHIV testingPrior diagnosisSubsequent referralReferral ratesHIV epidemicHIVTreatment centersChallenges to Achieving HCV Micro-Elimination in People With HIV in the United States: Provider Perspectives and the Role of Implicit Bias
DiDomizio E, Chandra D, Nichols L, Villanueva M, Altice F. Challenges to Achieving HCV Micro-Elimination in People With HIV in the United States: Provider Perspectives and the Role of Implicit Bias. Health Promotion Practice 2023, 24: 998-1008. PMID: 37440258, DOI: 10.1177/15248399231169928.Peer-Reviewed Original ResearchConceptsNominal group techniqueHealth care decisionsProvider perspectivesEligibility criteriaHIV/HCVEffective antiviral medicationsPatient eligibility criteriaFacilitators of treatmentMicro-EliminationHCV treatmentAntiviral medicationsOpioid epidemicProvider knowledgePatient involvementPatient engagementDifferent clinicsRelated stigmaHCVCare decisionsHIVPatientsTreatmentGroup sessionsMost barriersFocus group sessionsFuture Directions for HIV/HCV Care: Lessons Learned From Local Evaluation Projects in Texas and Connecticut and Implications for Practice and Health Promotion
Villanueva M. Future Directions for HIV/HCV Care: Lessons Learned From Local Evaluation Projects in Texas and Connecticut and Implications for Practice and Health Promotion. Health Promotion Practice 2023, 24: 1050-1054. PMID: 37439561, DOI: 10.1177/15248399231169919.Peer-Reviewed Original ResearchConceptsServices Administration's Special ProjectsHCV elimination goalsSystem-level barriersHCV careHCV cureHepatitis CElimination goalsHealth promotionYale University SchoolIndividualized approachPriority populationsLocal implementation strategiesLevel barriersUniversity SchoolImplementation strategiesHCVHIVPatientsSan AntonioEvaluation projectCareCreating a Longitudinal HCV Care Cascade for Persons With HIV/HCV Coinfection in Selected HIV Clinics Using Data to Care Methods
Brooks R, Wegener M, Speers S, Nichols L, Sideleau R, Valeriano T, Buchelli M, Villanueva M. Creating a Longitudinal HCV Care Cascade for Persons With HIV/HCV Coinfection in Selected HIV Clinics Using Data to Care Methods. Health Promotion Practice 2023, 24: 1039-1049. PMID: 37439600, DOI: 10.1177/15248399231169792.Peer-Reviewed Original ResearchConceptsHIV/HCV coinfectionHCV coinfectionHepatitis C virusSVR ratesHCV treatmentHIV clinicTreatment cascadeTreatment statusSustained virologic response ratesHCV care cascadeHCV treatment cascadeHCV treatment statusVirologic response ratesHIV viral suppressionPatient treatment statusPublic health approachCare cascadeHepatitis CViral suppressionActing antiviralsTreatment initiationC virusResponse rateClinical staffCoinfectionCharacterizing Persons With HIV/HCV Coinfection Who Remain Untreated for Hepatitis C at Four HIV Clinics in Connecticut (CT): Role of Multiple Overlapping Barriers at the Individual and Clinic System Levels
Zhao A, Wegener M, Brooks R, Mininberg L, Helou E, Maughan A, Villanueva M. Characterizing Persons With HIV/HCV Coinfection Who Remain Untreated for Hepatitis C at Four HIV Clinics in Connecticut (CT): Role of Multiple Overlapping Barriers at the Individual and Clinic System Levels. Health Promotion Practice 2023, 24: 1029-1038. PMID: 37439687, DOI: 10.1177/15248399231169793.Peer-Reviewed Original ResearchConceptsHIV/HCV coinfectionHepatitis C virusHCV coinfectionHIV clinicDirect-acting antiviral medicationsHIV transmission risk factorsPrimary care HIV clinicClinic-level barriersHCV elimination targetsChronic HCV infectionRetrospective chart reviewPatient-level barriersClinical practice patternsMedication-assisted treatmentTransmission risk factorsIllicit substance usePatient-specific issuesLack of transportationSubstance use problemsMental health issuesHCV cureHCV infectionHCV treatmentHepatitis CUntreated patientsExpanded or Risk Factor-Based Annual Screening for Hepatitis C Virus (HCV) Among Persons With HIV: Which Is the Best Approach?
Hao R, Brooks R, Zelenev A, Spinner G, Barakat L, Villanueva M. Expanded or Risk Factor-Based Annual Screening for Hepatitis C Virus (HCV) Among Persons With HIV: Which Is the Best Approach? Health Promotion Practice 2023, 24: 1009-1017. PMID: 37439817, DOI: 10.1177/15248399231169794.Peer-Reviewed Original ResearchConceptsHepatitis C virusRisk factor-based screeningElectronic medical recordsHIV clinicAnnual screeningC virusRisk factorsScreening siteAnnual screening ratesNew HCV diagnosesClinical decision support toolRisk factor assessmentPublic health expertsHCV testingHCV casesClinical decision supportHCV diagnosisHCV testScreening ratesProspective studyMedical recordsPositivity ratePositive casesUnprotected sexClinicThe Cooperative Re-Engagement Controlled Trial (CoRECT): Durable Viral Suppression Assessment
O'Shea J, Fanfair R, Williams T, Khalil G, Brady K, DeMaria A, Villanueva M, Randall L, Jenkins H, Altice F, Camp N, Lucas C, Buchelli M, Samandari T, Weidle P. The Cooperative Re-Engagement Controlled Trial (CoRECT): Durable Viral Suppression Assessment. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2023, 93: 134-142. PMID: 36812382, PMCID: PMC10962216, DOI: 10.1097/qai.0000000000003178.Peer-Reviewed Original ResearchConceptsDurable viral suppressionActive public health interventionProportion of PWHPublic health interventionsViral loadCare strategiesHealth interventionsLast viral loadCopies/mLStandard of careRace/ethnicityCare armHIV careViral suppressionAntiretroviral adherenceCD4 categoryExposure categoriesCare individualsPWHCareAge categoriesInterventionTrialsBirth sexRe-EngagementImplementing a Surveillance-Based Approach to Create a Statewide Viral Clearance Cascade for Hepatitis C Among People With HIV and HCV Coinfection in Connecticut
Wegener M, Brooks R, Speers S, Nichols L, Villanueva M. Implementing a Surveillance-Based Approach to Create a Statewide Viral Clearance Cascade for Hepatitis C Among People With HIV and HCV Coinfection in Connecticut. Public Health Reports 2023, 139: 208-217. PMID: 37232422, PMCID: PMC10851907, DOI: 10.1177/00333549231172173.Peer-Reviewed Original ResearchHIV viral loadHCV coinfectionViral loadSurveillance databaseUndetectable HIV viral loadDetectable HIV viral loadDisease controlHIV/AIDS Reporting SystemHCV elimination strategyRecent HIV testAIDS Reporting SystemElectronic Disease Surveillance SystemOutcomes of peoplePublic health departmentsDisease surveillance systemsSurveillance-based approachHCV cureHCV statusHepatitis CAntiviral medicationsHIV testC virusViral testingHealth departmentsInitial infectionCosts and cost‐effectiveness of a collaborative data‐to‐care intervention for HIV treatment and care in the United States
Shrestha R, Fanfair R, Randall L, Lucas C, Nichols L, Camp N, Brady K, Jenkins H, Altice F, DeMaria A, Villanueva M, Weidle P. Costs and cost‐effectiveness of a collaborative data‐to‐care intervention for HIV treatment and care in the United States. Journal Of The International AIDS Society 2023, 26: e26040. PMID: 36682053, PMCID: PMC9867888, DOI: 10.1002/jia2.26040.Peer-Reviewed Original ResearchConceptsCare armHIV careCare patientsIntervention armCare interventionsHealth departmentsHIV care interventionsHIV care outcomesHIV care providersHealthcare provider perspectiveHIV clinicHIV treatmentCare providersControl trialCare outcomesMicrocosting approachCare programCare servicesSurveillance dataSimilar interventionsIncremental costIntervention costsProvider perspectivesCareAverage costCosts and cost-effectiveness of a collaborative data to care intervention for HIV prevention in the US
Shrestha RK, Neblett Fanfair R, Randall L, Lucas C, Nichols L, Camp N, Brady K, Jenkins H, Altice F, Villanueva M, Demaria APeer-Reviewed Original ResearchThe Cooperative Re-Engagement Controlled Trial (CoRECT): Durable Viral Suppression Assessment
O’Shea J, Neblett Fanfair R, Williams T, Khalil G, Brady K, DeMaria A, Villanueva M, Randall L, Jenkins H, Altice F, Camp N, Lucas C, Buchelli M, Samandari T, Weidle PPeer-Reviewed Original Research In PressImplementing a Surveillance-Based Approach to Create a Statewide Viral Clearance Cascade for Hepatitis C Among People with HIV and HCV Coinfection in Connecticut
Wegener M, Brooks R, Speers S, Nichols L, Villanueva MPeer-Reviewed Original Research In PressUsing Learning Experience Design (LXD) to Promote Decreasing Stigma in Creating a Video Series about Syringe Services Programs (SSP)
Sims K, Wegener M, Nichols L, Villanueva M. Using Learning Experience Design (LXD) to Promote Decreasing Stigma in Creating a Video Series about Syringe Services Programs (SSP). Journal Of Applied Instructional Design 2023 DOI: 10.59668/515.12966.Peer-Reviewed Original Research