2019
Refeeding Syndrome in the Critically Ill: a Literature Review and Clinician’s Guide
McKnight C, Newberry C, Sarav M, Martindale R, Hurt R, Daley B. Refeeding Syndrome in the Critically Ill: a Literature Review and Clinician’s Guide. Current Gastroenterology Reports 2019, 21: 58. PMID: 31758276, DOI: 10.1007/s11894-019-0724-3.Peer-Reviewed Original ResearchMeSH KeywordsCritical IllnessEnteral NutritionHumansNutrition AssessmentParenteral NutritionRefeeding SyndromeRisk FactorsTreatment OutcomeConceptsRefeeding syndromeCritically ill patientsNational Institute for Health and Clinical Excellence criteriaAssessment toolDefinition of RFSNutrition care planModerate to severe malnutritionClinical assessment toolIll patientsCritically ill patient populationNutritional assessment toolManagement of refeeding syndromeDecrease complication ratesCare planningIll patient populationLife-threatening conditionMethods of diagnosisMetabolic teamComplication rateGastrointestinal complicationsClinician's GuideDecrease morbiditySevere malnutritionNutritional supportElectrolyte imbalance
2017
Summary Points and Consensus Recommendations From the International Protein Summit
Hurt R, McClave S, Martindale R, Gautier J, Coss‐Bu J, Dickerson R, Heyland D, Hoffer L, Moore F, Morris C, Paddon‐Jones D, Patel J, Phillips S, Rugeles S, Sarav M, Weijs P, Wernerman J, Hamilton‐Reeves J, McClain C, Taylor B. Summary Points and Consensus Recommendations From the International Protein Summit. Nutrition In Clinical Practice 2017, 32: 142s-151s. PMID: 28388374, DOI: 10.1177/0884533617693610.Peer-Reviewed Original ResearchMeSH KeywordsConsensusCritical IllnessDietary ProteinsHumansIntensive Care UnitsNutritional RequirementsNutritional StatusNutritional SupportConceptsIntensive care unitPhase of critical illnessHigh nutritional riskInitial phase of critical illnessCritically ill patientsHealthcare professionalsMammalian target of rapamycinNutritional riskImproved insulin sensitivityDose of proteinClinical nutritionProtein goalsMuscle massNutrition therapyHigh doses of proteinClinical outcomesProtein administrationTarget of rapamycinBody protein homeostasisSummary PointsMeeting energy goalsHigh dosesNew protein synthesisProtein doseConsensus recommendationsProtein Requirements for Critically Ill Patients With Renal and Liver Failure
Patel J, McClain C, Sarav M, Hamilton‐Reeves J, Hurt R. Protein Requirements for Critically Ill Patients With Renal and Liver Failure. Nutrition In Clinical Practice 2017, 32: 101s-111s. PMID: 28208022, DOI: 10.1177/0884533616687501.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryCritical IllnessDietary ProteinsHumansIntensive Care UnitsLiver FailureNutritional RequirementsConceptsDecompensated liver cirrhosisAcute kidney injuryAcute liver failureNegative nitrogen balanceMuscle wastingRenal replacement therapyCritically ill patientsRespiratory failureLiver dysfunctionReplacement therapyKidney injuryLiver failureLiver cirrhosisAmino acid lossesICU admissionIncreased riskOptimal protein supplementationSevere formIll patientsCritical illnessNitrogen balanceProtein abnormalitiesAssociated with proteolysisProtein requirementsAcid lossAcquired Amino Acid Deficiencies: A Focus on Arginine and Glutamine
Morris C, Hamilton‐Reeves J, Martindale R, Sarav M, Gautier J. Acquired Amino Acid Deficiencies: A Focus on Arginine and Glutamine. Nutrition In Clinical Practice 2017, 32: 30s-47s. PMID: 28388380, DOI: 10.1177/0884533617691250.Peer-Reviewed Original ResearchConceptsLow arginine bioavailabilityT cell dysfunctionAmino acidsSickle cell diseaseArginine bioavailabilityPulmonary hypertensionT cellsTherapeutic optionsConditionally essential amino acidsDeficiency syndromeCystic fibrosisEndothelial dysfunctionAcute asthmaAt-risk populationsCatabolic stateCell diseaseClinical scenariosAmino acid synthesisCritical illnessConditions of stressGastrointestinal disordersAcid deficiencyCardiovascular diseaseCatabolism of arginineSynthesized de novo