Contribution of Potentially Inappropriate Medications to Polypharmacy-Associated Risk of Mortality in Middle-Aged Patients: A National Cohort Study
Guillot J, Justice A, Gordon K, Skanderson M, Pariente A, Bezin J, Rentsch C. Contribution of Potentially Inappropriate Medications to Polypharmacy-Associated Risk of Mortality in Middle-Aged Patients: A National Cohort Study. Journal Of General Internal Medicine 2024, 1-10. PMID: 38831248, DOI: 10.1007/s11606-024-08817-4.Peer-Reviewed Original ResearchMiddle-aged patientsRisk of mortalityVeterans AffairsChronic medicationsVA patient populationIntegrated healthcare systemNational cohort studyAssociated with increased mortalityMiddle-aged individualsMechanism of injuryMiddle-aged peopleAssociated with mortalityInappropriate medicationsBeers criteriaHealthcare systemAttenuate riskCohort studyClinical characteristicsGeneral populationHyperpolypharmacyFollow-upPolypharmacyPatient populationBackgroundThe roleCox modelEstimating risk for pancreatic cancer among 9.4 million veterans in care.
Wang L, Rahimi Larki N, Skanderson M, Tate J, Hauser R, Brandt C, Yang Y, Justice A. Estimating risk for pancreatic cancer among 9.4 million veterans in care. Journal Of Clinical Oncology 2024, 42: 10544-10544. DOI: 10.1200/jco.2024.42.16_suppl.10544.Peer-Reviewed Original ResearchVeterans Health AdministrationGeneral populationAlcohol useIntegrated health systemElectronic health recordsTen-year riskHistory of cancerLoss to follow-upFollow-upEvaluated model discriminationMedian baseline ageCox proportional hazards modelsRisk prediction modelHealth recordsProportional hazards modelHealth systemHealth AdministrationMultivariate Cox proportional hazards modelSmoking statusCharlson Comorbidity IndexBaseline ageClinical reasoningRange of risksHazards modelFinal predictors