2022
Best Practice for Improving Sleep in the ICU. Part I: Non-pharmacologic
Korwin A, Knauert M. Best Practice for Improving Sleep in the ICU. Part I: Non-pharmacologic. 2022, 231-248. DOI: 10.1007/978-3-031-06447-0_14.ChaptersIntensive care unitICU patientsNormal sleepCritical care treatmentNon-pharmacologic therapiesNon-pharmacologic interventionsMost ICU patientsAbnormal circadian rhythmPoor quality sleepCircadian functionAcute illnessCritical illnessPatient characteristicsIll adultsCare unitChronotherapeutic interventionsCare treatmentSleep preferenceCurrent evidencePatient careCircadian disruptionSleepPatientsFuture interventionsPractice change
2020
Pilot Observational Study to Detect Diurnal Variation and Misalignment in Heart Rate Among Critically Ill Patients
Knauert MP, Murphy TE, Doyle MM, Pisani MA, Redeker NS, Yaggi HK. Pilot Observational Study to Detect Diurnal Variation and Misalignment in Heart Rate Among Critically Ill Patients. Frontiers In Neurology 2020, 11: 637. PMID: 32760341, PMCID: PMC7373742, DOI: 10.3389/fneur.2020.00637.Peer-Reviewed Original ResearchMedical ICU admissionIntensive care unitHeart rateIll patientsICU admissionCircadian alignmentMedical record chart abstractionsProspective observational cohort studyCircadian disruptionMedical ICU patientsObservational cohort studyCritical illness outcomesPilot observational studyContinuous telemetric monitoringChart abstractionExploratory analysisCohort studyCritical illnessHospital admissionICU patientsCare unitPatient interviewsFrequent bloodOdds ratioObservational study
2018
Association between death and loss of stage N2 sleep features among critically Ill patients with delirium
Knauert MP, Gilmore EJ, Murphy TE, Yaggi HK, Van Ness PH, Han L, Hirsch LJ, Pisani MA. Association between death and loss of stage N2 sleep features among critically Ill patients with delirium. Journal Of Critical Care 2018, 48: 124-129. PMID: 30179762, PMCID: PMC6226351, DOI: 10.1016/j.jcrc.2018.08.028.Peer-Reviewed Original ResearchConceptsICU patientsIll patientsOdds ratioHigher oddsSleep spindlesIntensive care unit outcomesGrade of encephalopathySignificant sleep disruptionWorse ICU outcomeMedical ICU patientsAcute brain injuryObservational cohort studySedative-hypnotic useImportant prognostic valueLength of stayStage N2 sleepK-complexesCohort studyCritical illnessHospital dischargeRankin ScaleICU outcomesPrognostic valueSevere gradesMedical recordsSurvey of clinical pharmacist perceptions and practices in promoting sleep in intensive care unit patients
Heavner M, Nguyen N, Knauert M, Verceles A, Pisani M, Seung H, Gonzales J. Survey of clinical pharmacist perceptions and practices in promoting sleep in intensive care unit patients. JACCP JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY 2018, 2: 46-52. DOI: 10.1002/jac5.1027.Peer-Reviewed Original ResearchIntensive care unitICU patientsResults Two hundred fiftyIntensive care unit patientsSurgical intensive care unitProtocol usePharmacists' perceptionsCritical care pharmacistsCare unit patientsICU patient outcomesSignificant patient morbidityMelatonin receptor agonistCritical care practiceCross-sectional surveySleep protocolDelirium incidenceUnit patientsNighttime administrationCare unitPatient morbidityCare pharmacistsICU practiceReceptor agonistHundred fiftyPatient outcomesCreating Naptime
Knauert MP, Redeker NS, Yaggi HK, Bennick M, Pisani MA. Creating Naptime. Journal Of Patient Experience 2018, 5: 180-187. PMID: 30214923, PMCID: PMC6134539, DOI: 10.1177/2374373517747242.Peer-Reviewed Original ResearchIntensive care unitLaboratory drawsICU deliriumPromotion protocolRest periodDuration of deliriumMedical ICU patientsMedical chart reviewBrief clustersChart reviewICU patientsRoutine careCare unitSleep promotionPatient anxietyProtocol violationsSleep disruptionUrgent carePilot protocolOvernight rest periodPatient disturbancePatient careDeliriumStakeholder feedbackCare
2016
Perceptions and Practices Regarding Sleep in the Intensive Care Unit. A Survey of 1,223 Critical Care Providers
Kamdar BB, Knauert MP, Jones SF, Parsons EC, Parthasarathy S, Pisani MA. Perceptions and Practices Regarding Sleep in the Intensive Care Unit. A Survey of 1,223 Critical Care Providers. Annals Of The American Thoracic Society 2016, 13: 1370-7. PMID: 27104770, PMCID: PMC5021080, DOI: 10.1513/annalsats.201601-087oc.Peer-Reviewed Original ResearchConceptsPoor sleepICU outcomesProviders' perceptionsIntensive care unit outcomesAvailable evidence-based guidelinesDevelopment of deliriumIntensive care unitEvidence-based guidelinesCritical care providersBetter sleep qualityMinority of providersICU surveyICU patientsIll patientsCare unitMechanical ventilationICU providersPatient outcomesRecent guidelinesPhysical therapyMost cliniciansPromotion protocolSleep qualityCare providersICU