2022
Impressions of sleep
Kryger M. Impressions of sleep. Sleep Health 2022, 8: 569-570. PMID: 36379844, DOI: 10.1016/j.sleh.2022.10.004.Commentaries, Editorials and Letters
2021
Comorbid Insomnia and Sleep Apnea: mechanisms and implications of an underrecognized and misinterpreted sleep disorder
Meira E Cruz M, Kryger MH, Morin CM, Palombini L, Salles C, Gozal D. Comorbid Insomnia and Sleep Apnea: mechanisms and implications of an underrecognized and misinterpreted sleep disorder. Sleep Medicine 2021, 84: 283-288. PMID: 34214960, DOI: 10.1016/j.sleep.2021.05.043.Peer-Reviewed Original ResearchMeSH KeywordsDisorders of Excessive SomnolenceHumansSleepSleep Apnea SyndromesSleep Initiation and Maintenance DisordersSleep Wake Disorders
2016
Jack London's Sleep.
Kryger M. Jack London's Sleep. Journal Of Clinical Sleep Medicine 2016, 12: 1545-1547. PMID: 27568902, PMCID: PMC5078710, DOI: 10.5664/jcsm.6286.Commentaries, Editorials and LettersAdultCaliforniaEarthquakesFamous PersonsHistory, 19th CenturyHistory, 20th CenturyHumansLiterature, ModernMaleSleepSleep Initiation and Maintenance DisordersStress Disorders, Post-TraumaticEffects of Suvorexant, an Orexin Receptor Antagonist, on Respiration during Sleep In Patients with Obstructive Sleep Apnea.
Sun H, Palcza J, Card D, Gipson A, Rosenberg R, Kryger M, Lines C, Wagner JA, Troyer MD. Effects of Suvorexant, an Orexin Receptor Antagonist, on Respiration during Sleep In Patients with Obstructive Sleep Apnea. Journal Of Clinical Sleep Medicine 2016, 12: 9-17. PMID: 26194728, PMCID: PMC4702197, DOI: 10.5664/jcsm.5382.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAzepinesCross-Over StudiesDouble-Blind MethodFemaleHumansMaleMiddle AgedOrexin Receptor AntagonistsPolysomnographyRespirationSleepSleep Apnea, ObstructiveSleep Initiation and Maintenance DisordersTriazolesYoung AdultConceptsObstructive sleep apneaOrexin receptor antagonistMean AHIRespiratory effectsSleep apneaMultiple dosesReceptor antagonistIntra-individual variabilityModerate obstructive sleep apneaEffects of suvorexantLowest effective doseSleep laboratory studiesTotal sleep timeMean SpO2Single doseRespiratory functionOxygen saturationPulse oximetryPlaceboPatientsSleep timeAHIDay 4Mean increaseSuvorexant
2008
The effects of ramelteon on respiration during sleep in subjects with moderate to severe chronic obstructive pulmonary disease
Kryger M, Roth T, Wang-Weigand S, Zhang J. The effects of ramelteon on respiration during sleep in subjects with moderate to severe chronic obstructive pulmonary disease. Sleep And Breathing 2008, 13: 79-84. PMID: 18584227, DOI: 10.1007/s11325-008-0196-4.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultComorbidityCross-Over StudiesDouble-Blind MethodFemaleHumansIndenesMaleOximetryPolysomnographyPulmonary Disease, Chronic ObstructiveReceptors, MelatoninSeverity of Illness IndexSleep Apnea SyndromesSleep Apnea, ObstructiveSleep Initiation and Maintenance DisordersSleep StagesYoung AdultConceptsSevere chronic obstructive pulmonary diseaseChronic obstructive pulmonary diseaseEffects of ramelteonObstructive pulmonary diseasePulmonary diseaseMean SaO2Respiratory depressant effectsApnea-hypopnea indexPoor sleep qualityTotal sleep timeMelatonin receptor agonistResultsNo significant differencesSignificant differencesAbnormal breathing eventsRamelteon 8Primary endpointAdverse eventsPersistent sleepCrossover studyDepressant effectPolysomnographic monitoringReceptor agonistRespiratory effortInsomnia treatmentSleep quality
2007
Safety of ramelteon in individuals with mild to moderate obstructive sleep apnea
Kryger M, Wang-Weigand S, Roth T. Safety of ramelteon in individuals with mild to moderate obstructive sleep apnea. Sleep And Breathing 2007, 11: 159-164. PMID: 17294232, DOI: 10.1007/s11325-006-0096-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultArousalDouble-Blind MethodFemaleHumansHypnotics and SedativesIndenesMaleMiddle AgedOxygenPolysomnographySleep Apnea, ObstructiveSleep Initiation and Maintenance DisordersSleep StagesWakefulnessConceptsObstructive sleep apneaNext-day residual effectsApnea-hypopnea indexSleep apneaPost-sleep questionnaireAdverse eventsSelective MT1/MT2 receptor agonistMT1/MT2 receptor agonistMT2 receptor agonistSafety of ramelteonUrinary tract infectionArterial oxygen saturationControl of breathingRespiratory inductance plethysmographyRamelteon groupPlacebo groupTract infectionsCrossover studyWashout periodDepressant effectSleep QuestionnaireHypopneic eventsRespiratory effortInsomnia treatmentOxygen saturation
2006
The burden of chronic insomnia on society.
Kryger MH. The burden of chronic insomnia on society. Managed Care 2006, 15: 1-5, 17. PMID: 17175621.Peer-Reviewed Original ResearchCost of IllnessHealth Care CostsHumansPrevalenceQuality of LifeSleep Initiation and Maintenance DisordersUnited States
2004
Sleep, health, and aging. Bridging the gap between science and clinical practice.
Kryger M, Monjan A, Bliwise D, Ancoli-Israel S. Sleep, health, and aging. Bridging the gap between science and clinical practice. Geriatrics 2004, 59: 24-6, 29-30. PMID: 14755865.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAccidental FallsAgedAgingFemaleHumansMaleSleep Initiation and Maintenance DisordersUrination DisordersConceptsExcessive daytime sleepinessPrevalence of insomniaProblems of sleepSlow-wave sleepQuality of lifeAdults age 65Age-related processesGeriatric populationDaytime sleepinessSleep disordersSleep efficiencyClinical practiceRestful sleepAge 65Depressed moodOlder populationSleepInsomniaLater lifeAdverse changesMemory problemsNight resultsComorbiditiesPopulationSleepiness
1991
Subjective Versus Objective Evaluation of Hypnotic Efficacy: Experience with Zolpidem
Kryger M, Steljes D, Pouliot Z, Neufeld H, Odynski T. Subjective Versus Objective Evaluation of Hypnotic Efficacy: Experience with Zolpidem. Sleep 1991, 14: 399-407. PMID: 1759092, DOI: 10.1093/sleep/14.5.399.Peer-Reviewed Original ResearchMeSH KeywordsAdultArousalElectroencephalographyFemaleHumansHypnotics and SedativesMaleMiddle AgedPyridinesReaction TimeSleep Initiation and Maintenance DisordersSleep StagesSubstance Withdrawal SyndromeWakefulnessZolpidemConceptsTotal sleep timeSleep latencyNumber of awakeningsSleep timePSG findingsPersistent sleepHypnotic efficacySleep qualityPatients' subjective evaluationSubjective sleep qualityDecreased sleep latencyQuality of sleepShortened sleep latencyTotal wake timeObjective measuresPolysomnographic findingsSleepy patientsChronic insomniaWeeks' useIndividual patientsSleep efficiencySubjective reductionSubjective increaseObjective efficacyPatients