2015
The Use of a Fully Automated Automatic Adaptive Servoventilation Algorithm in the Acute and Long-term Treatment of Central Sleep Apnea
Javaheri S, Winslow D, McCullough P, Wylie P, Kryger MH. The Use of a Fully Automated Automatic Adaptive Servoventilation Algorithm in the Acute and Long-term Treatment of Central Sleep Apnea. CHEST Journal 2015, 148: 1454-1461. PMID: 25950507, DOI: 10.1378/chest.14-2966.Peer-Reviewed Original ResearchConceptsCentral apnea indexApnea-hypopnea indexCentral sleep apneaSleep apneaSleep qualityComplex sleep-disordered breathingASV deviceASV titrationAdaptive servoventilation devicesCongestive heart failureMonths of treatmentSleep-disordered breathingEpworth Sleepiness ScaleLong-term treatmentImproved sleep qualityMixed sleep apneaBetter sleep qualityApnea indexHeart failureObservational trialObstructive apneaBreathing disordersInspiratory pressureArousal indexDaytime sleepiness
2007
Sleep apnea: Clinical investigations in humans
Banno K, Kryger MH. Sleep apnea: Clinical investigations in humans. Sleep Medicine 2007, 8: 400-426. PMID: 17478121, DOI: 10.1016/j.sleep.2007.03.003.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsObstructive sleep apnea syndromeCentral sleep apnea syndromeContinuous positive airway pressureSleep apnea syndromeApnea syndromeApneic episodesTreatment of OSASDiagnosis of SASUpper airway obstructionPositive airway pressureMuscles of respirationCessation of breathingCentral nervous systemAirway obstructionAirway pressureHeart failureOral appliancesRespiratory driveImpaired qualityAbnormal breathingSubjective symptomsDaytime sleepinessCommon disorderMetabolic dysfunctionSleep disruption
2005
Auto-Titrating Continuous Positive Airway Pressure for Heart Failure Patients With Cheyne-Stokes Respiration and Central Sleep Apnea
Banno K, Okamura K, Kryger MH. Auto-Titrating Continuous Positive Airway Pressure for Heart Failure Patients With Cheyne-Stokes Respiration and Central Sleep Apnea. Circulation Journal 2005, 69: 1295. PMID: 16200689, DOI: 10.1253/circj.69.1295.Peer-Reviewed Original ResearchMeSH KeywordsCheyne-Stokes RespirationHeart FailureHumansOximetryPositive-Pressure RespirationSleep Apnea Syndromes
1995
The Effects of Posture Change and Continuous Positive Airway Pressure on Cardiac Natriuretic Peptides in Congestive Heart Failure
Wilkins M, Su X, Palayew M, Yamashiro Y, Bolli P, McKenzie J, Kryger M. The Effects of Posture Change and Continuous Positive Airway Pressure on Cardiac Natriuretic Peptides in Congestive Heart Failure. CHEST Journal 1995, 107: 909-915. PMID: 7705152, DOI: 10.1378/chest.107.4.909.Peer-Reviewed Original ResearchConceptsCongestive heart failureAtrial natriuretic peptideN-CPAP therapyN-CPAPNatriuretic peptideHeart failureANP concentrationNasal continuous positive airway pressure therapyContinuous positive airway pressure therapyChronic congestive heart failureMean plasma ANP concentrationPositive airway pressure therapyContinuous positive airway pressureUpright postureAirway pressure therapyPositive airway pressureMean levelsPeripheral plasma levelsPlasma ANP concentrationCardiac natriuretic peptidesAirway pressureBNP concentrationsPressure therapyPlasma levelsPatients
1994
Ventilatory Instability in Patients With Congestive Heart Failure and Nocturnal Cheyne-Stokes Breathing
Ahmed M, Serrette C, Kryger M, Anthonisen N. Ventilatory Instability in Patients With Congestive Heart Failure and Nocturnal Cheyne-Stokes Breathing. Sleep 1994, 17: 527-534. PMID: 7809566, DOI: 10.1093/sleep/17.6.527.Peer-Reviewed Original ResearchConceptsCongestive heart failureCheyne-Stokes breathingAir-breathing controlsShort-term potentiationHeart failureCirculatory delayAge-matched normalsEnd-tidal CO2Air-breathing levelsAlveolar hypoxiaCHF patientsHyperoxic ventilationVentilatory instabilityVentilatory patternHypoxic hyperventilationPatient ventilationBreathing controlBreathing patternPatientsHyperoxiaVentilationHypoxiaProlonged circulation timeCompared resultsBrief exposureEffect of Inhaled 3% CO2 on Cheyne-Stokes Respiration in Congestive Heart Failure
Steens R, Millar T, Xiaoling S, Biberdorf D, Buckle P, Ahmed M, Kryger M. Effect of Inhaled 3% CO2 on Cheyne-Stokes Respiration in Congestive Heart Failure. Sleep 1994, 17: 61-68. PMID: 8191204, DOI: 10.1093/sleep/17.1.61.Peer-Reviewed Original ResearchConceptsStable congestive heart failureCheyne-Stokes respirationCongestive heart failureInhalation of CO2Heart failureSleep timeNocturnal arterial oxygen desaturationNight polysomnographic studiesArterial oxygen desaturationMovement sleep timeTotal sleep timeApnea indexOxygen desaturationMost patientsPolysomnographic studySleep latencySleep disruptionClinical significanceCardiac diseaseSleep structurePatientsNeurological diseasesNight 3Virtual abolitionShort duration
1993
Benzodiazepines in Congestive Heart Failure: Effects of Temazepam on Arousability and Cheyne-Stokes Respiration
Biberdorf D, Steens R, Millar T, Kryger M. Benzodiazepines in Congestive Heart Failure: Effects of Temazepam on Arousability and Cheyne-Stokes Respiration. Sleep 1993, 16: 529-538. PMID: 8235237, DOI: 10.1093/sleep/16.6.529.Peer-Reviewed Original ResearchConceptsCheyne-Stokes respirationCongestive heart failureTotal sleep timePercentage of TSTApnea/hypopnea indexOxygen saturationTotal wake timeEffects of temazepamHeart failureSleep architectureDouble-blind crossover trialSevere congestive heart failureOvernight oxygen saturationStage 1 sleepHours of sleepSleep stage proportionsCHF patientsHypopnea indexMale patientsDaytime somnolenceCrossover trialSignificant changesFrequent arousalsDaytime alertnessSleep timeReview: Sleep in Heart Failure
Yamashiro Y, Kryger M. Review: Sleep in Heart Failure. Sleep 1993, 16: 513-523. PMID: 8235235, DOI: 10.1093/sleep/16.6.513.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
1992
The Effect of Short-term Nasal CPAP on Cheyne-Stokes Respiration in Congestive Heart Failure
Buckle P, Millar T, Kryger M. The Effect of Short-term Nasal CPAP on Cheyne-Stokes Respiration in Congestive Heart Failure. CHEST Journal 1992, 102: 31-35. PMID: 1623779, DOI: 10.1378/chest.102.1.31.Peer-Reviewed Original ResearchMeSH KeywordsAdultCheyne-Stokes RespirationHeart FailureHumansMaleMiddle AgedNoseOxygenPositive-Pressure RespirationSleepConceptsCongestive heart failureCheyne-Stokes respirationMultiple sleep latency testNasal CPAPSleep qualityNocturnal oxygenationHeart failureTreatment nightsDaytime arterial blood gas valuesArterial blood gas valuesNasal CPAP therapyNYHA class 3Sleep latency testBlood gas valuesShort-term treatmentSignificant differencesAge 54.1CPAP therapyMale patientsFull polysomnographyDaytime sleepinessLatency testCPAPPatientsGas values
1990
The Entrainment of Low Frequency Breathing Periodicity
Millar T, Hardy P, Hunt B, Frais M, Kryger M. The Entrainment of Low Frequency Breathing Periodicity. CHEST Journal 1990, 98: 1143-1148. PMID: 2225959, DOI: 10.1378/chest.98.5.1143.Peer-Reviewed Original ResearchSleep and heart failure.
Kryger M. Sleep and heart failure. European Respiratory Journal 1990, 3: 1103-4. PMID: 2090470, DOI: 10.1183/09031936.93.03101103.Peer-Reviewed Original ResearchCheyne-Stokes respiration in cardiac failure.
Kryger M, Hanly P. Cheyne-Stokes respiration in cardiac failure. Progress In Clinical And Biological Research 1990, 345: 215-24; discussion 224-6. PMID: 2377634.Peer-Reviewed Original Research
1989
The effect of oxygen on respiration and sleep in patients with congestive heart failure.
Hanly P, Millar T, Steljes D, Baert R, Frais M, Kryger M. The effect of oxygen on respiration and sleep in patients with congestive heart failure. Annals Of Internal Medicine 1989, 111: 777-82. PMID: 2817624, DOI: 10.7326/0003-4819-111-10-777.Peer-Reviewed Original ResearchConceptsStable congestive heart failureCheyne-Stokes respirationCongestive heart failureHeart failureTotal sleep timeOxygen therapySleep timeStage 1 NREM sleepPlacebo-controlled crossover studyLow-flow oxygenNocturnal oxygen saturationNocturnal oxygen therapyOutpatient cardiology clinicApnea-hypopnea indexNumber of arousalsStage 1 sleepStage 2 sleepSlow-wave sleepHyperpneic phaseNocturnal hypoxemiaSleep hypoxemiaMale patientsNasal cannulaeCardiology clinicCrossover studyRespiration and Abnormal Sleep in Patients with Congestive Heart Failure
Hanly B, Millar T, Steljes D, Boert R, Frais M, Kryger M. Respiration and Abnormal Sleep in Patients with Congestive Heart Failure. CHEST Journal 1989, 96: 480-488. PMID: 2766808, DOI: 10.1378/chest.96.3.480.Peer-Reviewed Original ResearchConceptsCheyne-Stokes respirationCongestive heart failureStage 2 NREM sleepSlow-wave sleepSleep stage changesNREM sleepHyperpneic phaseHeart failureREM sleepAwake arterial oxygen saturationStable congestive heart failureSevere congestive heart failureStage 1Mean minimum SaO2Outcomes of patientsNumber of arousalsArterial oxygen saturationStage 1 sleepMinimum SaO2Severe hypoxemiaArterial oxygenationSignificant hypoxemiaClinical statusMean durationAbnormal sleep