2015
The Use of a Fully Automated Automatic Adaptive Servoventilation Algorithm in the Acute and Long-term Treatment of Central Sleep Apnea
Javaheri S, Winslow D, McCullough P, Wylie P, Kryger MH. The Use of a Fully Automated Automatic Adaptive Servoventilation Algorithm in the Acute and Long-term Treatment of Central Sleep Apnea. CHEST Journal 2015, 148: 1454-1461. PMID: 25950507, DOI: 10.1378/chest.14-2966.Peer-Reviewed Original ResearchConceptsCentral apnea indexApnea-hypopnea indexCentral sleep apneaSleep apneaSleep qualityComplex sleep-disordered breathingASV deviceASV titrationAdaptive servoventilation devicesCongestive heart failureMonths of treatmentSleep-disordered breathingEpworth Sleepiness ScaleLong-term treatmentImproved sleep qualityMixed sleep apneaBetter sleep qualityApnea indexHeart failureObservational trialObstructive apneaBreathing disordersInspiratory pressureArousal indexDaytime sleepiness
2011
Long-term use of a nasal expiratory positive airway pressure (EPAP) device as a treatment for obstructive sleep apnea (OSA).
Kryger MH, Berry RB, Massie CA. Long-term use of a nasal expiratory positive airway pressure (EPAP) device as a treatment for obstructive sleep apnea (OSA). Journal Of Clinical Sleep Medicine 2011, 7: 449-53b. PMID: 22003339, PMCID: PMC3190843, DOI: 10.5664/jcsm.1304.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaPositive airway pressure devicesMonths of treatmentSleep apneaObstructive sleep apnea hypopneaOpen-label extensionPositive clinical responseEvents/hLong-term adherenceSleep disorders centerEpworth Sleepiness ScaleSleep apnea hypopneaPressure deviceLong-term useAHI reductionClinical responseMonth 3Randomized studyApnea hypopneaMedian AHITrial nameClinical trialsMonths 1Disorders CenterSham trialsA Novel Nasal Expiratory Positive Airway Pressure (EPAP) Device for the Treatment of Obstructive Sleep Apnea: A Randomized Controlled Trial
Berry RB, Kryger MH, Massie CA. A Novel Nasal Expiratory Positive Airway Pressure (EPAP) Device for the Treatment of Obstructive Sleep Apnea: A Randomized Controlled Trial. Sleep 2011, 34: 479-485. PMID: 21461326, PMCID: PMC3065258, DOI: 10.1093/sleep/34.4.479.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaPositive airway pressure devicesSleep apneaSham deviceWeek 1Double-blind clinical trialSevere obstructive sleep apneaMonths of treatmentSleep disorders centerEpworth Sleepiness ScalePressure deviceSubjective daytime sleepinessNon-consecutive nightsControlled TrialsMonth 3Sham treatmentClinical trialsDaytime sleepinessITT groupDisorders CenterSleepiness ScaleAHI valuesApneaMedian percentageAHI
2001
Radiofrequency tissue reduction of the palate in patients with moderate sleep-disordered breathing.
Brown D, Kerr P, Kryger M. Radiofrequency tissue reduction of the palate in patients with moderate sleep-disordered breathing. Journal Of Otolaryngology 2001, 30: 193-8. PMID: 11771028, DOI: 10.2310/7070.2001.19696.Peer-Reviewed Original ResearchMeSH KeywordsAdultCatheter AblationHumansMaleMiddle AgedPalate, SoftPolysomnographyProspective StudiesSleep Apnea, ObstructiveTreatment OutcomeConceptsModerate sleep-disordered breathingSleep-disordered breathingApnea-hypopnea indexMild sleep-disordered breathingRadiofrequency tissue ablationRadiofrequency tissue reductionSt. Boniface HospitalClinically significant differencesResponse to treatmentEpworth Sleepiness ScalePost-treatment groupSoft palate tissueApnea-HypopneaArousal indexClinical efficacyEffects of treatmentPalatal tissueSoft palateFollow-upTissue reductionDaytime sleepinessRadiofrequency energySleepiness ScalePatientsSleep parameters
1999
Health Care Utilization in Males with Obstructive Sleep Apnea Syndrome Two Years After Diagnosis and Treatment
Bahammam A, Delaive K, Ronald J, Manfreda J, Roos L, Kryger M. Health Care Utilization in Males with Obstructive Sleep Apnea Syndrome Two Years After Diagnosis and Treatment. Sleep 1999, 22: 740-747. PMID: 10505819, DOI: 10.1093/sleep/22.6.740.Peer-Reviewed Original ResearchConceptsOSA patientsGeneral populationProspective observational cohort studyObservational cohort studySubgroup of patientsSleep disorders centerTreatment of patientsTwo yearsOSAS groupCohort studyPAT groupControl subjectsDisorders CenterPhysician claimsPatientsUtilization dataOne-yearDiagnosisYears one yearTreatmentYearsCanadian provincesOSASGroupHospital
1997
Using Self-Reported Questionnaire Data to Prioritize OSA Patients for Polysomnography
Pouliot Z, Peters M, Neufeld H, Kryger M. Using Self-Reported Questionnaire Data to Prioritize OSA Patients for Polysomnography. Sleep 1997, 20: 232-236. PMID: 9178919, DOI: 10.1093/sleep/20.3.232.Peer-Reviewed Original ResearchConceptsBody mass indexEpworth Sleepiness ScaleObstructive sleep apneaSimple clinical dataPercent of casesAnalysis of receiverHundreds of patientsLow AIObserved apneaApnea indexOSA patientsConsecutive patientsSleep apneaMass indexSelf-reported questionnaire dataClinical dataSleepiness ScalePatientsApneaPolysomnographyCharacteristic curveQuestionnaire dataGroupQuestionnaireSubjects
1996
Treatment of Obstructive Sleep Apnea With a Self-Titrating Continuous Positive Airway Pressure (CPAP) System
Sharma S, Wali S, Pouliot Z, Peters M, Neufeld H, Kryger M. Treatment of Obstructive Sleep Apnea With a Self-Titrating Continuous Positive Airway Pressure (CPAP) System. Sleep 1996, 19: 497-501. PMID: 8865508, DOI: 10.1093/sleep/19.6.497.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalysis of VarianceFemaleHumansMaleMiddle AgedPositive-Pressure RespirationProspective StudiesPulmonary VentilationSleep Apnea SyndromesConceptsContinuous positive airway pressureCPAP nightCPAP systemLowest arterial oxygen saturationObstructive sleep apnea syndromeContinuous positive airway pressure systemDiagnostic sleep studyNasal CPAP systemPositive airway pressureProspective clinical trialsObstructive sleep apneaSleep apnea syndromeSleep-disordered breathingArterial oxygen saturationMeasures of oxygenationTotal sleep timeLong-term useAirway pressureCPAP titrationSevere OSAAcute treatmentApnea syndromeSleep apneaArousal indexAirway stability
1993
Nasal Continuous Positive Airway Pressure
Kerr P, Shoenut J, Steens R, Millar T, Micflikier A, Kryger M. Nasal Continuous Positive Airway Pressure. Journal Of Clinical Gastroenterology 1993, 17: 276-280. PMID: 8308210, DOI: 10.1097/00004836-199312000-00002.Peer-Reviewed Original ResearchConceptsNasal continuous positive airway pressureContinuous positive airway pressureNocturnal gastroesophageal refluxLower esophageal pressurePositive airway pressureGastroesophageal refluxReflux patientsAirway pressureEsophageal pressureObstructive sleep apnea syndrome (OSAS) patientsSleep apnea syndrome patientsMean reflux durationNon-OSA patientsHealthy adult volunteersCPAP effectsNocturnal refluxEsophageal manometryMean durationIntraesophageal pressureLongest refluxSyndrome patientsHealthy volunteersReflux durationPatientsAdult volunteers
1978
Flexible Fiberoptic Bronchoscopy in the Teaching Hospital Yield and Complications
Dreisin R, Albert R, Talley P, Kryger M, Scoggin C, Zwillich C. Flexible Fiberoptic Bronchoscopy in the Teaching Hospital Yield and Complications. CHEST Journal 1978, 74: 144-149. PMID: 679742, DOI: 10.1378/chest.74.2.144.Peer-Reviewed Original ResearchConceptsFiberoptic bronchoscopic proceduresBronchoscopic proceduresMalignant neoplasmsRate of complicationsFlexible fiberoptic bronchoscopyLobar atelectasisSevere bronchospasmAsthmatic patientsImmunosuppressed patientsTherapeutic subgroupsFiberoptic bronchoscopyTransbronchial biopsyPeripheral nodulesPulmonary disordersBronchoscopic lavageFiberoptic bronchoscopeInflammatory diseasesTeaching hospitalPatientsNormal hostsComplicationsOverall rateNeoplasmsPercentReliable tool