2019
Centers for Medicare and Medicaid Services Positive Airway Pressure Adherence Criteria May Limit Treatment to Many Medicare Beneficiaries.
Naik S, Al-Halawani M, Kreinin I, Kryger M. Centers for Medicare and Medicaid Services Positive Airway Pressure Adherence Criteria May Limit Treatment to Many Medicare Beneficiaries. Journal Of Clinical Sleep Medicine 2019, 15: 245-251. PMID: 30736874, PMCID: PMC6374085, DOI: 10.5664/jcsm.7626.Peer-Reviewed Original ResearchConceptsEvents/hAdherence criteriaPAP treatmentObstructive sleep apnea treatmentPositive airway pressure devicesWithholding of therapyApnea-hypopnea indexObstructive sleep apneaSleep apnea treatmentMedicaid Services reimbursementAdherence reportsBaseline characteristicsPAP devicesPAP adherenceAdherent participantsApnea treatmentSleep apneaNonadherent participantsAdherence dataMedicare beneficiariesAdherence patternsCMS criteriaAdherence expectationsPatientsMonths
2016
Positive Airway Pressure Therapy for Obstructive Sleep Apnea
Weiss P, Kryger M. Positive Airway Pressure Therapy for Obstructive Sleep Apnea. Otolaryngologic Clinics Of North America 2016, 49: 1331-1341. PMID: 27720457, DOI: 10.1016/j.otc.2016.07.004.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsContinuity of Patient CareContinuous Positive Airway PressureHumansPatient CompliancePositive-Pressure RespirationSleep Apnea, ObstructiveConceptsPositive airway pressureObstructive sleep apneaAirway pressureSleep apneaMild obstructive sleep apneaPositive airway pressure therapyContinuous positive airway pressureSevere obstructive sleep apneaObstructive sleep apnea syndromeSleep-related breathing disordersConcomitant cardiovascular disordersAirway pressure therapyFirst-line therapySleep apnea syndromeAdaptive support ventilationEvaluation of adherenceEffectiveness of treatmentApnea syndromeSupport ventilationBreathing disordersPressure therapyCardiovascular disordersApneaTherapyPressure support
2012
Respiratory Event Detection by a Positive Airway Pressure Device
Berry RB, Kushida CA, Kryger MH, Soto-Calderon H, Staley B, Kuna ST. Respiratory Event Detection by a Positive Airway Pressure Device. Sleep 2012, 35: 361-367. PMID: 22379242, PMCID: PMC3274337, DOI: 10.5665/sleep.1696.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaEvents/hrPositive airway pressure devicesApnea indexHypopnea indexPAP devicesRespiratory eventsSleep disorders centerPressure deviceBetter treatment efficacyRespiratory event detectionOxygen desaturationSleep apneaPAP treatmentBland-Altman analysisDisorders CenterPolysomnographyTreatment efficacyAHIInadequate treatmentManual scoringHypopnea detectionTrue negative eventsHrTreatment
2011
Long-term use of a nasal expiratory positive airway pressure (EPAP) device as a treatment for obstructive sleep apnea (OSA).
Kryger MH, Berry RB, Massie CA. Long-term use of a nasal expiratory positive airway pressure (EPAP) device as a treatment for obstructive sleep apnea (OSA). Journal Of Clinical Sleep Medicine 2011, 7: 449-53b. PMID: 22003339, PMCID: PMC3190843, DOI: 10.5664/jcsm.1304.Peer-Reviewed Original ResearchMeSH KeywordsCohort StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedPatient CompliancePolysomnographyPositive-Pressure RespirationProspective StudiesSleep Apnea, ObstructiveTimeTreatment OutcomeConceptsObstructive sleep apneaPositive airway pressure devicesMonths of treatmentSleep apneaObstructive sleep apnea hypopneaOpen-label extensionPositive clinical responseEvents/hLong-term adherenceSleep disorders centerEpworth Sleepiness ScaleSleep apnea hypopneaPressure deviceLong-term useAHI reductionClinical responseMonth 3Randomized studyApnea hypopneaMedian AHITrial nameClinical trialsMonths 1Disorders CenterSham trialsA Novel Nasal Expiratory Positive Airway Pressure (EPAP) Device for the Treatment of Obstructive Sleep Apnea: A Randomized Controlled Trial
Berry RB, Kryger MH, Massie CA. A Novel Nasal Expiratory Positive Airway Pressure (EPAP) Device for the Treatment of Obstructive Sleep Apnea: A Randomized Controlled Trial. Sleep 2011, 34: 479-485. PMID: 21461326, PMCID: PMC3065258, DOI: 10.1093/sleep/34.4.479.Peer-Reviewed Original ResearchMeSH KeywordsDouble-Blind MethodFemaleHumansMaleMiddle AgedPolysomnographyPositive-Pressure RespirationProspective StudiesSleepSleep Apnea, ObstructiveTreatment OutcomeConceptsObstructive sleep apneaPositive airway pressure devicesSleep apneaSham deviceWeek 1Double-blind clinical trialSevere obstructive sleep apneaMonths of treatmentSleep disorders centerEpworth Sleepiness ScalePressure deviceSubjective daytime sleepinessNon-consecutive nightsControlled TrialsMonth 3Sham treatmentClinical trialsDaytime sleepinessITT groupDisorders CenterSleepiness ScaleAHI valuesApneaMedian percentageAHI
2005
Auto-Titrating Continuous Positive Airway Pressure for Heart Failure Patients With Cheyne-Stokes Respiration and Central Sleep Apnea
Banno K, Okamura K, Kryger MH. Auto-Titrating Continuous Positive Airway Pressure for Heart Failure Patients With Cheyne-Stokes Respiration and Central Sleep Apnea. Circulation Journal 2005, 69: 1295. PMID: 16200689, DOI: 10.1253/circj.69.1295.Peer-Reviewed Original ResearchMeSH KeywordsCheyne-Stokes RespirationHeart FailureHumansOximetryPositive-Pressure RespirationSleep Apnea Syndromes
2004
Reducing Motor-Vehicle Collisions, Costs, and Fatalities by Treating Obstructive Sleep Apnea Syndrome
Sassani A, Findley LJ, Kryger M, Goldlust E, George C, Davidson TM. Reducing Motor-Vehicle Collisions, Costs, and Fatalities by Treating Obstructive Sleep Apnea Syndrome. Sleep 2004, 27: 453-458. PMID: 15164898, DOI: 10.1093/sleep/27.3.453.Peer-Reviewed Original Research
2003
Sleep Disorders in a Military Population
Pouliot Z, Peters M, Neufeld H, Delaive K, Kryger M. Sleep Disorders in a Military Population. Military Medicine 2003, 168: 7-10. PMID: 12546237, DOI: 10.1093/miled.168.1.7.Peer-Reviewed Original ResearchMeSH KeywordsAdultCanadaCase-Control StudiesFemaleHumansIncidenceMaleMilitary PersonnelPolysomnographyPositive-Pressure RespirationRisk FactorsSleep Wake DisordersConceptsSleep breathing disordersSleep disordersMovement disordersMilitary populationExcessive daytime sleepinessSleep disorders centerMajority of referralsCanadian military personnelMilitary personnelCommon diagnosisBreathing disordersMean ageFull polysomnographyMilitary patientsSleep diagnosesDaytime sleepinessDisorders CenterNeurocognitive impairmentDisordersCivilian populationDiagnosisAgeGroupSDPopulation
2002
What data do we need to diagnose and treat obstructive sleep apnoea syndrome?
Kryger M. What data do we need to diagnose and treat obstructive sleep apnoea syndrome? Sleep Medicine Reviews 2002, 6: 3-6. PMID: 12531137, DOI: 10.1053/smrv.2001.0222.Peer-Reviewed Original Research
1998
Susceptibility of LDL to Oxidative Stress in Obstructive Sleep Apnea
Wali S, Bahammam A, Massaeli H, Pierce G, Iliskovic N, Singal P, Kryger M. Susceptibility of LDL to Oxidative Stress in Obstructive Sleep Apnea. Sleep 1998, 21: 290-296. PMID: 9595608, DOI: 10.1093/sleep/21.3.290.Peer-Reviewed Original ResearchConceptsLow-density lipoproteinObstructive sleep apneaOSA patientsNormal controlsOxidative stressSleep apneaPatient groupSevere hypoxiaSusceptibility of LDLFree radical challengeSame age groupCPAP therapySevere hypoxemiaRed blood cellsCardiovascular diseaseAntioxidant reserveGeneral populationPatientsIndividual low-density lipoproteinHours of exposureControl groupAge groupsGlutathione peroxidaseBlood cellsConjugated dienes
1997
Controversies in Sleep Medicine: Terminology and Definitions in Sleep-Disordered Breathing
Kryger M. Controversies in Sleep Medicine: Terminology and Definitions in Sleep-Disordered Breathing. Sleep 1997, 20: 1208-1208. PMID: 9493934, DOI: 10.1093/sleep/20.12.1208.Peer-Reviewed Original ResearchSleep apnoea and the misuse of evidence-based medicine
Kryger M. Sleep apnoea and the misuse of evidence-based medicine. The Lancet 1997, 349: 803-804. PMID: 9074596, DOI: 10.1016/s0140-6736(05)60232-2.Commentaries, Editorials and LettersEvidence-Based MedicineHumansPositive-Pressure RespirationSleep Apnea SyndromesState MedicineUnited Kingdom
1996
Treatment of Obstructive Sleep Apnea With a Self-Titrating Continuous Positive Airway Pressure (CPAP) System
Sharma S, Wali S, Pouliot Z, Peters M, Neufeld H, Kryger M. Treatment of Obstructive Sleep Apnea With a Self-Titrating Continuous Positive Airway Pressure (CPAP) System. Sleep 1996, 19: 497-501. PMID: 8865508, DOI: 10.1093/sleep/19.6.497.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalysis of VarianceFemaleHumansMaleMiddle AgedPositive-Pressure RespirationProspective StudiesPulmonary VentilationSleep Apnea SyndromesConceptsContinuous positive airway pressureCPAP nightCPAP systemLowest arterial oxygen saturationObstructive sleep apnea syndromeContinuous positive airway pressure systemDiagnostic sleep studyNasal CPAP systemPositive airway pressureProspective clinical trialsObstructive sleep apneaSleep apnea syndromeSleep-disordered breathingArterial oxygen saturationMeasures of oxygenationTotal sleep timeLong-term useAirway pressureCPAP titrationSevere OSAAcute treatmentApnea syndromeSleep apneaArousal indexAirway stability
1995
Medical treatment of sleep apnea
Wali S, Kryger M. Medical treatment of sleep apnea. Current Opinion In Pulmonary Medicine 1995, 1: 498-503. PMID: 9363089, DOI: 10.1097/00063198-199511000-00012.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSleep apneaContinuous positive airway pressure therapyPositive airway pressure therapyContinuous positive airway pressureAirway pressure therapyPositive airway pressureObstructive sleep apneaCurrent treatment optionsTreatment of choiceAirway pressureNicotine treatmentPressure therapyTreatment optionsCommon disorderMedical treatmentDifficult patientsElectrical stimulationWeight lossDental appliancesApneaTherapyTreatmentUnwanted effectsTracheostomyPatientsSuccessful Treatment of Comorbid Panic Disorder and Sleep Apnea With Continuous Positive Airway Pressure
Enns M, Stein M, Kryger M. Successful Treatment of Comorbid Panic Disorder and Sleep Apnea With Continuous Positive Airway Pressure. Journal Of The Academy Of Consultation-Liaison Psychiatry 1995, 36: 585-586. PMID: 7501792, DOI: 10.1016/s0033-3182(95)71620-6.Peer-Reviewed Original ResearchThe Effects of Posture Change and Continuous Positive Airway Pressure on Cardiac Natriuretic Peptides in Congestive Heart Failure
Wilkins M, Su X, Palayew M, Yamashiro Y, Bolli P, McKenzie J, Kryger M. The Effects of Posture Change and Continuous Positive Airway Pressure on Cardiac Natriuretic Peptides in Congestive Heart Failure. CHEST Journal 1995, 107: 909-915. PMID: 7705152, DOI: 10.1378/chest.107.4.909.Peer-Reviewed Original ResearchMeSH KeywordsAgedAtrial Natriuretic FactorFemaleHeart FailureHumansMaleMiddle AgedNatriuretic Peptide, BrainNerve Tissue ProteinsPositive-Pressure RespirationPostureConceptsCongestive heart failureAtrial natriuretic peptideN-CPAP therapyN-CPAPNatriuretic peptideHeart failureANP concentrationNasal continuous positive airway pressure therapyContinuous positive airway pressure therapyChronic congestive heart failureMean plasma ANP concentrationPositive airway pressure therapyContinuous positive airway pressureUpright postureAirway pressure therapyPositive airway pressureMean levelsPeripheral plasma levelsPlasma ANP concentrationCardiac natriuretic peptidesAirway pressureBNP concentrationsPressure therapyPlasma levelsPatients
1994
The Effect of Nasal CPAP on Nocturnal Reflux in Patients With Aperistaltic Esophagus
Shoenut J, Kerr P, Micflikier A, Yamashiro Y, Kryger M. The Effect of Nasal CPAP on Nocturnal Reflux in Patients With Aperistaltic Esophagus. CHEST Journal 1994, 106: 738-741. PMID: 8082351, DOI: 10.1378/chest.106.3.738.Peer-Reviewed Original ResearchConceptsNocturnal refluxNasal CPAPAperistaltic esophagusLES pressureReflux eventsNasal continuous positive airway pressureContinuous positive airway pressureLower esophageal sphincter pressurePositive airway pressureEsophageal sphincter pressureGroup of patientsScleroderma esophagusScleroderma groupAirway pressureSphincter pressureSleep apneaPercentage of timeCPAPPatientsSecond nightRefluxEsophagusFirst nightAchalasiaGroupAcute Effect of Nasal CPAP on Periodic Limb Movements Associated with Breathing Disorders During Sleep
Yamashiro Y, Kryger M. Acute Effect of Nasal CPAP on Periodic Limb Movements Associated with Breathing Disorders During Sleep. Sleep 1994, 17: 172-175. PMID: 8036372, DOI: 10.1093/sleep/17.2.172.Peer-Reviewed Original ResearchMeSH KeywordsAdultExtremitiesFemaleHumansMaleMiddle AgedMovementPositive-Pressure RespirationRespiration DisordersSleep Apnea SyndromesSleep Wake DisordersConceptsNasal continuous positive airway pressurePeriodic limb movementsSleep-disordered breathingPLMS indexAcute effectsContinuous positive airway pressureLimb movementsSplit-night protocolPositive airway pressureNCPAP treatmentNasal CPAPAirway pressureBreathing disordersBreathingTreatmentFuture investigationsApneaCPAPPatientsSleep
1993
Nasal Continuous Positive Airway Pressure
Kerr P, Shoenut J, Steens R, Millar T, Micflikier A, Kryger M. Nasal Continuous Positive Airway Pressure. Journal Of Clinical Gastroenterology 1993, 17: 276-280. PMID: 8308210, DOI: 10.1097/00004836-199312000-00002.Peer-Reviewed Original ResearchConceptsNasal continuous positive airway pressureContinuous positive airway pressureNocturnal gastroesophageal refluxLower esophageal pressurePositive airway pressureGastroesophageal refluxReflux patientsAirway pressureEsophageal pressureObstructive sleep apnea syndrome (OSAS) patientsSleep apnea syndrome patientsMean reflux durationNon-OSA patientsHealthy adult volunteersCPAP effectsNocturnal refluxEsophageal manometryMean durationIntraesophageal pressureLongest refluxSyndrome patientsHealthy volunteersReflux durationPatientsAdult volunteersReview: Sleep in Heart Failure
Yamashiro Y, Kryger M. Review: Sleep in Heart Failure. Sleep 1993, 16: 513-523. PMID: 8235235, DOI: 10.1093/sleep/16.6.513.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements