1997
Using Self-Reported Questionnaire Data to Prioritize OSA Patients for Polysomnography
Pouliot Z, Peters M, Neufeld H, Kryger M. Using Self-Reported Questionnaire Data to Prioritize OSA Patients for Polysomnography. Sleep 1997, 20: 232-236. PMID: 9178919, DOI: 10.1093/sleep/20.3.232.Peer-Reviewed Original ResearchConceptsBody mass indexEpworth Sleepiness ScaleObstructive sleep apneaSimple clinical dataPercent of casesAnalysis of receiverHundreds of patientsLow AIObserved apneaApnea indexOSA patientsConsecutive patientsSleep apneaMass indexSelf-reported questionnaire dataClinical dataSleepiness ScalePatientsApneaPolysomnographyCharacteristic curveQuestionnaire dataGroupQuestionnaireSubjects
1995
Irregular breathing during sleep in patients with panic disorder
Stein M, Millar T, Larsen D, Kryger M. Irregular breathing during sleep in patients with panic disorder. American Journal Of Psychiatry 1995, 152: 1168-1173. PMID: 7625465, DOI: 10.1176/ajp.152.8.1168.Peer-Reviewed Original ResearchConceptsHealthy comparison subjectsPanic disorderComparison subjectsIrregular breathingSleep panic attacksSubgroup of patientsMedication-free patientsNocturnal breathing patternsNocturnal breathingSleep breathingNight of sleepRespiratory irregularitiesTidal volumeVentilatory variabilityBreathing patternPatientsAwake statePanic attacksSubtle disordersBreathingDisordersSleepSleep samplesPossible relationshipSubjects
1993
A Developmental Study of the Dose-Response Curve of the Respiratory Sensory Reflex
Alvaro R, De Almeida V, Kwiatkowski K, Cates D, Kryger M, Rigatto H. A Developmental Study of the Dose-Response Curve of the Respiratory Sensory Reflex. American Journal Of Respiratory And Critical Care Medicine 1993, 148: 1013-1017. PMID: 8214918, DOI: 10.1164/ajrccm/148.4_pt_1.1013.Peer-Reviewed Original Research
1987
Snoring in Normal Young Adults: Prevalence in Sleep Stages and Associated Changes in Oxygen Saturation, Heart Rate, and Breathing Pattern
Perez-Padilla J, West P, Kryger M. Snoring in Normal Young Adults: Prevalence in Sleep Stages and Associated Changes in Oxygen Saturation, Heart Rate, and Breathing Pattern. Sleep 1987, 10: 249-253. PMID: 3629087, DOI: 10.1093/sleep/10.3.249.Peer-Reviewed Original ResearchConceptsHeart rateContinuous snoringSleep stagesOxygen saturationPrevalence of snoringSignificant O2 desaturationMean heart rateNormal young adultsMean SaO2O2 desaturationDifferent pathogenesisDifferent sleep stagesNormal subjectsBreathing patternLight snorersBreathing frequencySnoringArrhythmiasYoung adultsPrevalenceStage 3Same sleep stageStage 2Associated ChangesSubjects
1976
Clinical Semi-Starvation — Depression of Hypoxic Ventilatory Response
Doekel R, Zwillich C, Scoggin C, Kryger M, Weil J. Clinical Semi-Starvation — Depression of Hypoxic Ventilatory Response. New England Journal Of Medicine 1976, 295: 358-361. PMID: 819829, DOI: 10.1056/nejm197608122950703.Peer-Reviewed Original ResearchConceptsHypoxic ventilatory responseVentilatory responseHypercapnic ventilatory responseMetabolic rateRespiratory failureIntravenous fluidsDecreased metabolic rateCarbohydrate dietNormal subjectsCaloric restrictionDay 10HypercapniaSupplemental electrolytesResponse responseSubjectsResponseHypoxemiaDecreaseHypoxiaAlimentationEffect of Meperidine on Occlusion Pressure Responses to Hypercapnia and Hypoxia with and without External Inspiratory Resistance1–3
Kryger M, Yacoub O, Dosman J, Macklem P, Anthonisen N. Effect of Meperidine on Occlusion Pressure Responses to Hypercapnia and Hypoxia with and without External Inspiratory Resistance1–3. American Journal Of Respiratory And Critical Care Medicine 1976, 114: 333-40. PMID: 973724, DOI: 10.1164/arrd.1976.114.2.333.Peer-Reviewed Original ResearchConceptsInspiratory resistanceNormal subjectsOcclusion pressure responsesInspiratory motor outputEffect of meperidineOral meperidineVentilatory responseAcute increaseInspiratory effortClosed airwayMeperidineHypercapniaProgressive hypoxiaMotor outputMore depressionHypoxiaHypoxic responsePressure responseP0.1Combination of resistanceSubjectsResponseAirwayExercise tolerance at 4 and 6 ATA.
Anthonisen N, Utz G, Kryger M, Urbanetti J. Exercise tolerance at 4 and 6 ATA. Undersea And Hyperbaric Medicine 1976, 3: 95-112. PMID: 951829.Peer-Reviewed Original ResearchConceptsDisturbance of consciousnessNormal male subjectsMaximum breathing capacityMaximum oxygen uptakeMaximum O2 uptakeO2 uptakeSevere dyspneaATA O2Bicycle exerciseLarge airwaysMinute ventilationHeavy exerciseHeart rateExercise levelsMale subjectsN2 narcosisRespiratory frequencyBreathing capacityCO2 retentionOxygen uptakeVentilationSubjectsATAExerciseCO2 output