2022
PAP Therapy for Sleep Breathing Disorders: Good Policies and Practices
Ali M, Kryger M. PAP Therapy for Sleep Breathing Disorders: Good Policies and Practices. 2022, 95-100. DOI: 10.1007/978-3-030-93146-9_8.ChaptersSleep-disordered breathingPAP adherencePAP therapyPositive airway pressure therapyExtensive patient educationAirway pressure therapySevere sleep apneaSleep breathing disordersTreatment of choiceLong-term usePAP initiationPAP usagePAP useSleep apneaBreathing disordersPressure therapySymptomatic burdenPAP complianceAdequate adherencePatient educationOptimal managementPoor maskPatientsTherapySocioeconomic status
2021
Comorbid Insomnia and Sleep Apnea: mechanisms and implications of an underrecognized and misinterpreted sleep disorder
Meira E Cruz M, Kryger MH, Morin CM, Palombini L, Salles C, Gozal D. Comorbid Insomnia and Sleep Apnea: mechanisms and implications of an underrecognized and misinterpreted sleep disorder. Sleep Medicine 2021, 84: 283-288. PMID: 34214960, DOI: 10.1016/j.sleep.2021.05.043.Peer-Reviewed Original Research
2018
Treating Sleep-Related Breathing Disorders
Won C, Mohsenin V, Kryger M. Treating Sleep-Related Breathing Disorders. 2018, 105-123. DOI: 10.1007/978-1-4939-8607-1_9.Peer-Reviewed Original ResearchPositive airway pressure therapySignificant symptomatic benefitAirway pressure therapySleep-disordered breathingMental health outcomesNeuropsychomotor functionsPAP therapyMainstay treatmentSymptomatic benefitPAP adherenceBreathing disordersPressure therapySide effectsHealth outcomesPatientsTherapyEffective alternativeAdherenceRobust evidenceTolerabilityBreathingSleep
2015
The Use of a Fully Automated Automatic Adaptive Servoventilation Algorithm in the Acute and Long-term Treatment of Central Sleep Apnea
Javaheri S, Winslow D, McCullough P, Wylie P, Kryger MH. The Use of a Fully Automated Automatic Adaptive Servoventilation Algorithm in the Acute and Long-term Treatment of Central Sleep Apnea. CHEST Journal 2015, 148: 1454-1461. PMID: 25950507, DOI: 10.1378/chest.14-2966.Peer-Reviewed Original ResearchConceptsCentral apnea indexApnea-hypopnea indexCentral sleep apneaSleep apneaSleep qualityComplex sleep-disordered breathingASV deviceASV titrationAdaptive servoventilation devicesCongestive heart failureMonths of treatmentSleep-disordered breathingEpworth Sleepiness ScaleLong-term treatmentImproved sleep qualityMixed sleep apneaBetter sleep qualityApnea indexHeart failureObservational trialObstructive apneaBreathing disordersInspiratory pressureArousal indexDaytime sleepiness
2008
Assessment and Management of Patients with Obesity Hypoventilation Syndrome
Mokhlesi B, Kryger MH, Grunstein RR. Assessment and Management of Patients with Obesity Hypoventilation Syndrome. Annals Of The American Thoracic Society 2008, 5: 218-225. PMID: 18250215, PMCID: PMC2645254, DOI: 10.1513/pats.200708-122mg.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsObesity hypoventilation syndromeSleep-disordered breathingHypoventilation syndromeManagement of patientsAvailable treatment modalitiesRelated health care expendituresSerious cardiovascular diseaseHealth care expensesHealth care expendituresDaytime hypercapniaEucapnic patientsSignificant lungClinical characteristicsObese patientsSignificant morbidityEarly mortalityTreatment modalitiesEarly recognitionExtreme obesityCardiovascular diseaseHigh burdenEffective treatmentHigh riskHigh indexClinical practice
2007
Obstructive Sleep Apnea in Pregnancy
Kapsimalis F, Kryger M. Obstructive Sleep Apnea in Pregnancy. Sleep Medicine Clinics 2007, 2: 603-613. DOI: 10.1016/j.jsmc.2007.07.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsObstructive sleep apnea syndromeSleep-disordered breathingPregnant womenTreatment of OSASDiagnosis of OSASTreatment of SDBObese pregnant womenComplications of pregnancyOutcome of pregnancyObstructive sleep apneaSleep apnea syndromeManagement of pregnancyApnea syndromeSleep apneaHormonal alterationsFetal healthEarly recognitionHigh indexPregnancyNormal sleepRespiratory systemWomenTreatmentHypertensionApnea
2005
Increasing obesity trends in patients with sleep-disordered breathing referred to a sleep disorders center.
Banno K, Walld R, Kryger MH. Increasing obesity trends in patients with sleep-disordered breathing referred to a sleep disorders center. Journal Of Clinical Sleep Medicine 2005, 1: 364-6. PMID: 17564402, DOI: 10.5664/jcsm.26362.Peer-Reviewed Original ResearchConceptsSleep-related breathing disordersBody mass indexSleep disorders centerMean body mass indexDisorders CenterBMI unitsObesity trendsSleep-disordered breathingPrevalence of obesityTime of referralYear of referralNumber of patientsMale patientsFemale patientsMass indexBreathing disordersMean ageNew patientsPatientsSignificant positive correlationReferralWomenObesityRegression analysisSex
2001
Radiofrequency tissue reduction of the palate in patients with moderate sleep-disordered breathing.
Brown D, Kerr P, Kryger M. Radiofrequency tissue reduction of the palate in patients with moderate sleep-disordered breathing. Journal Of Otolaryngology 2001, 30: 193-8. PMID: 11771028, DOI: 10.2310/7070.2001.19696.Peer-Reviewed Original ResearchConceptsModerate sleep-disordered breathingSleep-disordered breathingApnea-hypopnea indexMild sleep-disordered breathingRadiofrequency tissue ablationRadiofrequency tissue reductionSt. Boniface HospitalClinically significant differencesResponse to treatmentEpworth Sleepiness ScalePost-treatment groupSoft palate tissueApnea-HypopneaArousal indexClinical efficacyEffects of treatmentPalatal tissueSoft palateFollow-upTissue reductionDaytime sleepinessRadiofrequency energySleepiness ScalePatientsSleep parameters
1999
Blood Flow of the Middle Cerebral Artery With Sleep-Disordered Breathing: Correlation With Obstructive Hypopneas
Leslie W, Wali S, Kryger M. Blood Flow of the Middle Cerebral Artery With Sleep-Disordered Breathing: Correlation With Obstructive Hypopneas. Stroke 1999, 30: 188-90. PMID: 9880413, DOI: 10.1161/str.30.1.188/a.Peer-Reviewed Original Research
1996
Treatment of Obstructive Sleep Apnea With a Self-Titrating Continuous Positive Airway Pressure (CPAP) System
Sharma S, Wali S, Pouliot Z, Peters M, Neufeld H, Kryger M. Treatment of Obstructive Sleep Apnea With a Self-Titrating Continuous Positive Airway Pressure (CPAP) System. Sleep 1996, 19: 497-501. PMID: 8865508, DOI: 10.1093/sleep/19.6.497.Peer-Reviewed Original ResearchConceptsContinuous positive airway pressureCPAP nightCPAP systemLowest arterial oxygen saturationObstructive sleep apnea syndromeContinuous positive airway pressure systemDiagnostic sleep studyNasal CPAP systemPositive airway pressureProspective clinical trialsObstructive sleep apneaSleep apnea syndromeSleep-disordered breathingArterial oxygen saturationMeasures of oxygenationTotal sleep timeLong-term useAirway pressureCPAP titrationSevere OSAAcute treatmentApnea syndromeSleep apneaArousal indexAirway stability
1994
Acute Effect of Nasal CPAP on Periodic Limb Movements Associated with Breathing Disorders During Sleep
Yamashiro Y, Kryger M. Acute Effect of Nasal CPAP on Periodic Limb Movements Associated with Breathing Disorders During Sleep. Sleep 1994, 17: 172-175. PMID: 8036372, DOI: 10.1093/sleep/17.2.172.Peer-Reviewed Original ResearchConceptsNasal continuous positive airway pressurePeriodic limb movementsSleep-disordered breathingPLMS indexAcute effectsContinuous positive airway pressureLimb movementsSplit-night protocolPositive airway pressureNCPAP treatmentNasal CPAPAirway pressureBreathing disordersBreathingTreatmentFuture investigationsApneaCPAPPatientsSleep
1991
Central sleep apnoea in congenital muscular dystrophy.
Kryger M, Steljes D, Yee W, Mate E, Smith S, Mahowald M. Central sleep apnoea in congenital muscular dystrophy. Journal Of Neurology Neurosurgery & Psychiatry 1991, 54: 710. PMID: 1940943, PMCID: PMC1014476, DOI: 10.1136/jnnp.54.8.710.Peer-Reviewed Original ResearchConceptsCentral sleep apnoeaSleep-disordered breathingCongenital muscular dystrophyMorning headachesSleep apnoeaNocturnal seizuresCongestive heart failureMuscular dystrophyPulmonary hypertensionClinical weaknessHeart failureExcessive daytimeNeuromuscular syndromeRespiratory dysfunctionNeuromuscular disordersApnoeaHeadacheSeizuresSymptomsBreathingDystrophyHypertensionDysfunctionSyndrome