2000
Restless legs syndrome in 218 patients: associated disorders
Banno K, Delaive K, Walld R, Kryger M. Restless legs syndrome in 218 patients: associated disorders. Sleep Medicine 2000, 1: 221-229. PMID: 10828433, DOI: 10.1016/s1389-9457(00)00023-x.Peer-Reviewed Original ResearchRestless legs syndromeRLS patientsFemale controlsMale controlsMale patientsFemale patientsManitoba Health databasePeriodic limb movementsSleep laboratory evaluationSleep maintenance insomniaDiseases of jointsMost patientsExtrapyramidal diseasesRestless legsExtrapyramidal disordersLegs syndromePainful conditionsControl subjectsMaintenance insomniaMovement disordersGeneral populationPsychiatric disordersMusculoskeletal disordersPatientsHealth databases
1998
Effect of Pergolide on Restless Legs and Leg Movements in Sleep in Uremic Patients
Pieta J, Miliar T, Zacharias J, Fine A, Kryger M. Effect of Pergolide on Restless Legs and Leg Movements in Sleep in Uremic Patients. Sleep 1998, 21: 617-622. PMID: 9779521, DOI: 10.1093/sleep/21.6.617.Peer-Reviewed Original ResearchConceptsRestless legs syndromeLeg movementsRestless legsUremic patientsSubjective improvementTreatment of RLSDouble-blind placebo-controlled crossover studyPlacebo-controlled crossover studyRestless legs symptomsEffects of pergolideContinuous peritoneal dialysisPeriodic limb movementsSmall patient groupsHours of sleepQuality of sleepFirst hourChronic hemodialysisLeg symptomsCrossover studyLegs syndromePeritoneal dialysisIncremental dosesPatient groupSleep architectureSleep disruption
1996
L-DOPA/Carbidopa for Nocturnal Movement Disorders in Uremia
Walker S, Fine A, Kryger M. L-DOPA/Carbidopa for Nocturnal Movement Disorders in Uremia. Sleep 1996, 19: 214-218. PMID: 8723378, DOI: 10.1093/sleep/19.3.214.Peer-Reviewed Original ResearchConceptsL-dopa/carbidopaRestless legs syndromeSlow-wave sleepLeg movementsSleep timeTreatment of RLSMovement arousal indexNocturnal movement disordersSingle bedtime doseChronic hemodialysis patientsPeriodic limb movementsHours of sleepBedtime doseActive medicationHemodialysis patientsCrossover studyLegs syndromeUremic patientsArousal indexMovement disordersSleep disruptionFrequent dosingObjective improvementSleep disordersEffective treatment
1995
A Familial Awake Movement Disorder Mimicking Restless Legs in a Sleep Apnea Patient
Yamashiro Y, Chodirker B, Hobson D, Kryger M. A Familial Awake Movement Disorder Mimicking Restless Legs in a Sleep Apnea Patient. Sleep 1995, 18: 604-607. PMID: 8552932, DOI: 10.1093/sleep/18.7.604.Peer-Reviewed Original ResearchConceptsRestless legs syndromeMovement disordersFamilial movement disordersLegs syndromeSleep apneaNasal continuous positive airway pressureContinuous positive airway pressurePositive airway pressureObstructive sleep apneaPeriodic limb movementsSleep apnea syndromeSleep apnea patientsSleep onset insomniaSupine posturingAirway pressureObese menApnea syndromeLeg sensationsRestless legsNocturnal arousalsMean durationApnea patientsDaytime sleepinessSuccessful treatmentClinical significanceNocturnal Oximetry: Is It a Screening Tool for Sleep Disorders?
Yamashiro Y, Kryger M. Nocturnal Oximetry: Is It a Screening Tool for Sleep Disorders? Sleep 1995, 18: 167-171. PMID: 7610312, DOI: 10.1093/sleep/18.3.167.Peer-Reviewed Original ResearchConceptsUpper airway resistance syndromeExcessive daytime sleepinessHome oximetrySleep disordersSevere OSA patientsTertiary referral hospitalPeriodic limb movementsSleep disorders centerNumber of desaturationsSleep-breathing disordersDisorders of sleepOxygen saturation dataMild OSAOSA patientsPolysomnographic diagnosisReferral hospitalSleep apneaResistance syndromeDaytime sleepinessDisorders CenterBlinded comparisonClinical diagnosisOximetryPolysomnographyPatients
1994
Acute Effect of Nasal CPAP on Periodic Limb Movements Associated with Breathing Disorders During Sleep
Yamashiro Y, Kryger M. Acute Effect of Nasal CPAP on Periodic Limb Movements Associated with Breathing Disorders During Sleep. Sleep 1994, 17: 172-175. PMID: 8036372, DOI: 10.1093/sleep/17.2.172.Peer-Reviewed Original ResearchConceptsNasal continuous positive airway pressurePeriodic limb movementsSleep-disordered breathingPLMS indexAcute effectsContinuous positive airway pressureLimb movementsSplit-night protocolPositive airway pressureNCPAP treatmentNasal CPAPAirway pressureBreathing disordersBreathingTreatmentFuture investigationsApneaCPAPPatientsSleep