1989
Heart Rate Response to Breath-Hold, Valsalva and Mueller Maneuvers in Obstructive Sleep Apnea
Hanly P, George C, Millar T, Kryger M. Heart Rate Response to Breath-Hold, Valsalva and Mueller Maneuvers in Obstructive Sleep Apnea. CHEST Journal 1989, 95: 735-739. PMID: 2924602, DOI: 10.1378/chest.95.4.735.Peer-Reviewed Original ResearchConceptsVoluntary respiratory maneuversObstructive sleep apneaHR responseSleep apneaRespiratory maneuversMueller maneuverOxygen saturationVagal toneAbsence of hypoxemiaArterial oxygen saturationHeart rate responseObstructive apneaMouth pressureApneaHR changesMale subjectsRate responseBreath holdSimilar durationValsalvaSignificant differencesSignificant correlationOSASMajor determinantWakefulness
1976
Exercise tolerance at 4 and 6 ATA.
Anthonisen N, Utz G, Kryger M, Urbanetti J. Exercise tolerance at 4 and 6 ATA. Undersea And Hyperbaric Medicine 1976, 3: 95-112. PMID: 951829.Peer-Reviewed Original ResearchConceptsDisturbance of consciousnessNormal male subjectsMaximum breathing capacityMaximum oxygen uptakeMaximum O2 uptakeO2 uptakeSevere dyspneaATA O2Bicycle exerciseLarge airwaysMinute ventilationHeavy exerciseHeart rateExercise levelsMale subjectsN2 narcosisRespiratory frequencyBreathing capacityCO2 retentionOxygen uptakeVentilationSubjectsATAExerciseCO2 output