1991
Effect of Theophylline on Lung Function Tests, Sleep Quality, and Nighttime SaO2 in Children with Cystic Fibrosis
Avital A, Sanchez I, Holbrow J, Kryger M, Chernick V. Effect of Theophylline on Lung Function Tests, Sleep Quality, and Nighttime SaO2 in Children with Cystic Fibrosis. American Journal Of Respiratory And Critical Care Medicine 1991, 144: 1245-1249. PMID: 1741534, DOI: 10.1164/ajrccm/144.6.1245.Peer-Reviewed Original ResearchConceptsEffect of theophyllineCystic fibrosisMicrograms/Heart rateGroup 2Better baseline lung functionT blood levelsBaseline lung functionIncidence of apneaLung function testsSerum T levelsLower heart rateTotal wake timePulmonary functionLung functionSerum levelsFunction testsMean SaO2Blood levelsSleep qualitySleep efficiencyGroup 1Sleep laboratoryT levelsWake time
1980
Sleep Breathing Abnormalities in Kyphoscoliosis1–3
Mezon B, West P, Israels J, Kryger M. Sleep Breathing Abnormalities in Kyphoscoliosis1–3. American Journal Of Respiratory And Critical Care Medicine 1980, 122: 617-21. PMID: 7436128, DOI: 10.1164/arrd.1980.122.4.617.Peer-Reviewed Original ResearchConceptsBreathing abnormalitiesGreater oxygen desaturationPulmonary function testsArterial oxygen saturationCor pulmonaleChronic hypoxemiaOxygen desaturationCentral apneaFunction testsClinical evidencePhysiologic disturbancesSevere kyphoscoliosisMovement sleepSevere derangementThoracic deformityArterial PCO2Oxygen saturationSevere episodesChemical driveAbnormalitiesSleepPatientsDerangementPulmonaleHypoxemia