Benzodiazepines in Congestive Heart Failure: Effects of Temazepam on Arousability and Cheyne-Stokes Respiration
Biberdorf D, Steens R, Millar T, Kryger M. Benzodiazepines in Congestive Heart Failure: Effects of Temazepam on Arousability and Cheyne-Stokes Respiration. Sleep 1993, 16: 529-538. PMID: 8235237, DOI: 10.1093/sleep/16.6.529.Peer-Reviewed Original ResearchConceptsCheyne-Stokes respirationCongestive heart failureTotal sleep timePercentage of TSTApnea/hypopnea indexOxygen saturationTotal wake timeEffects of temazepamHeart failureSleep architectureDouble-blind crossover trialSevere congestive heart failureOvernight oxygen saturationStage 1 sleepHours of sleepSleep stage proportionsCHF patientsHypopnea indexMale patientsDaytime somnolenceCrossover trialSignificant changesFrequent arousalsDaytime alertnessSleep time