2015
The Use of a Fully Automated Automatic Adaptive Servoventilation Algorithm in the Acute and Long-term Treatment of Central Sleep Apnea
Javaheri S, Winslow D, McCullough P, Wylie P, Kryger MH. The Use of a Fully Automated Automatic Adaptive Servoventilation Algorithm in the Acute and Long-term Treatment of Central Sleep Apnea. CHEST Journal 2015, 148: 1454-1461. PMID: 25950507, DOI: 10.1378/chest.14-2966.Peer-Reviewed Original ResearchConceptsCentral apnea indexApnea-hypopnea indexCentral sleep apneaSleep apneaSleep qualityComplex sleep-disordered breathingASV deviceASV titrationAdaptive servoventilation devicesCongestive heart failureMonths of treatmentSleep-disordered breathingEpworth Sleepiness ScaleLong-term treatmentImproved sleep qualityMixed sleep apneaBetter sleep qualityApnea indexHeart failureObservational trialObstructive apneaBreathing disordersInspiratory pressureArousal indexDaytime sleepiness
2012
Respiratory Event Detection by a Positive Airway Pressure Device
Berry RB, Kushida CA, Kryger MH, Soto-Calderon H, Staley B, Kuna ST. Respiratory Event Detection by a Positive Airway Pressure Device. Sleep 2012, 35: 361-367. PMID: 22379242, PMCID: PMC3274337, DOI: 10.5665/sleep.1696.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaEvents/hrPositive airway pressure devicesApnea indexHypopnea indexPAP devicesRespiratory eventsSleep disorders centerPressure deviceBetter treatment efficacyRespiratory event detectionOxygen desaturationSleep apneaPAP treatmentBland-Altman analysisDisorders CenterPolysomnographyTreatment efficacyAHIInadequate treatmentManual scoringHypopnea detectionTrue negative eventsHrTreatment
1997
Using Self-Reported Questionnaire Data to Prioritize OSA Patients for Polysomnography
Pouliot Z, Peters M, Neufeld H, Kryger M. Using Self-Reported Questionnaire Data to Prioritize OSA Patients for Polysomnography. Sleep 1997, 20: 232-236. PMID: 9178919, DOI: 10.1093/sleep/20.3.232.Peer-Reviewed Original ResearchConceptsBody mass indexEpworth Sleepiness ScaleObstructive sleep apneaSimple clinical dataPercent of casesAnalysis of receiverHundreds of patientsLow AIObserved apneaApnea indexOSA patientsConsecutive patientsSleep apneaMass indexSelf-reported questionnaire dataClinical dataSleepiness ScalePatientsApneaPolysomnographyCharacteristic curveQuestionnaire dataGroupQuestionnaireSubjects
1994
Effect of Inhaled 3% CO2 on Cheyne-Stokes Respiration in Congestive Heart Failure
Steens R, Millar T, Xiaoling S, Biberdorf D, Buckle P, Ahmed M, Kryger M. Effect of Inhaled 3% CO2 on Cheyne-Stokes Respiration in Congestive Heart Failure. Sleep 1994, 17: 61-68. PMID: 8191204, DOI: 10.1093/sleep/17.1.61.Peer-Reviewed Original ResearchConceptsStable congestive heart failureCheyne-Stokes respirationCongestive heart failureInhalation of CO2Heart failureSleep timeNocturnal arterial oxygen desaturationNight polysomnographic studiesArterial oxygen desaturationMovement sleep timeTotal sleep timeApnea indexOxygen desaturationMost patientsPolysomnographic studySleep latencySleep disruptionClinical significanceCardiac diseaseSleep structurePatientsNeurological diseasesNight 3Virtual abolitionShort duration
1992
Short Technical Note: Quantification of Periodic Breathing: Preliminary Studies
Millar T, Hanly P, Kryger M. Short Technical Note: Quantification of Periodic Breathing: Preliminary Studies. Sleep 1992, 15: 364-370. PMID: 1519013, DOI: 10.1093/sleep/15.4.364.Peer-Reviewed Original ResearchConceptsApnea/hypopnea indexPeriodic breathingHypopnea indexBreathing patternPattern abnormalitiesHeart failure patientsCheyne-Stokes respirationNight sleep studiesApnea indexFailure patientsPatient populationIndividual patientsSleep studiesPeriodicity indexSleep laboratoryBreathingPatientsAbnormalitiesSleepSpectral analytic techniquesFuture studiesHigh correlationPreliminary studyIndexApnea
1988
Mortality and Apnea Index in Obstructive Sleep Apnea Experience in 385 Male Patients
He J, Kryger M, Zorick F, Conway W, Roth T. Mortality and Apnea Index in Obstructive Sleep Apnea Experience in 385 Male Patients. CHEST Journal 1988, 94: 9-14. PMID: 3289839, DOI: 10.1378/chest.94.1.9.Peer-Reviewed Original ResearchConceptsApnea indexObstructive sleep apneaNasal CPAPOSA patientsCumulative survivalObstructive sleep apnea experienceEight-year survivalMale OSAS patientsUntreated OSA patientsGreater mortalityYears of ageUPPP patientsLatter patientsMale patientsSleep apneaPatientsSurvival curvesMortalityTracheostomyCPAPSurvivalIndexApneaUPPPTherapy