Cytokines and normal sleep
Kapsimalis F, Richardson G, Opp MR, Kryger M. Cytokines and normal sleep. Current Opinion In Pulmonary Medicine 2005, 11: 481-484. PMID: 16217172, DOI: 10.1097/01.mcp.0000183062.98665.6b.Peer-Reviewed Original ResearchConceptsNon-rapid eye movement sleepEye movement sleepNeurohormonal systemsMovement sleepSpontaneous non-rapid eye movement sleepMultiple biologic actionsHypothalamic preoptic areaReceptor-mediated effectsTumor necrosis factorNitric oxide synthesisEffects of cytokinesDirect receptor-mediated effectsImmune system responseMechanism of actionSleep-wake regulationSite of actionAdrenal axisBasal forebrainPreoptic areaNecrosis factorInterleukin-1Adrenal axesNormal sleepCytokinesOxide synthesis