2022
Comparison of Ring Pulse Oximetry Using Reflective Photoplethysmography and PSG in the Detection of OSA in Chinese Adults: A Pilot Study
Zhao R, Xue J, Zhang X, Peng M, Li J, Zhou B, Zhao L, Penzel T, Kryger M, Dong XS, Gao Z, Han F. Comparison of Ring Pulse Oximetry Using Reflective Photoplethysmography and PSG in the Detection of OSA in Chinese Adults: A Pilot Study. Nature And Science Of Sleep 2022, 14: 1427-1436. PMID: 36003191, PMCID: PMC9394522, DOI: 10.2147/nss.s367400.Peer-Reviewed Original ResearchEvents/hOxygen desaturation indexIntraclass correlation coefficientPulse oximetryChinese adultsThreshold of AHIObstructive sleep apneaDetection of OSAPositive likelihood ratioChinese Han subjectsOxygen desaturationDesaturation indexSleep apneaMean ageSimultaneous polysomnographyOxygen saturationPSG-AHIPolysomnographySleep laboratorySleep timePilot studyHan subjectsAHIOximetryCumulative percentage
2016
Effects of Suvorexant, an Orexin Receptor Antagonist, on Respiration during Sleep In Patients with Obstructive Sleep Apnea.
Sun H, Palcza J, Card D, Gipson A, Rosenberg R, Kryger M, Lines C, Wagner JA, Troyer MD. Effects of Suvorexant, an Orexin Receptor Antagonist, on Respiration during Sleep In Patients with Obstructive Sleep Apnea. Journal Of Clinical Sleep Medicine 2016, 12: 9-17. PMID: 26194728, PMCID: PMC4702197, DOI: 10.5664/jcsm.5382.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaOrexin receptor antagonistMean AHIRespiratory effectsSleep apneaMultiple dosesReceptor antagonistIntra-individual variabilityModerate obstructive sleep apneaEffects of suvorexantLowest effective doseSleep laboratory studiesTotal sleep timeMean SpO2Single doseRespiratory functionOxygen saturationPulse oximetryPlaceboPatientsSleep timeAHIDay 4Mean increaseSuvorexant
2014
Evaluation of a new pediatric positive airway pressure mask.
Kushida CA, Halbower AC, Kryger MH, Pelayo R, Assalone V, Cardell CY, Huston S, Willes L, Wimms AJ, Mendoza J. Evaluation of a new pediatric positive airway pressure mask. Journal Of Clinical Sleep Medicine 2014, 10: 979-84. PMID: 25142768, PMCID: PMC4153116, DOI: 10.5664/jcsm.4030.Peer-Reviewed Original ResearchConceptsContinuous positive airway pressurePAP therapyPositive airway pressure maskPositive airway pressureParents/guardiansAirway pressureBaseline polysomnographyCPAP maskChildren's earsPressure maskPatientsAge groupsChildren's sleepUpper lipPolysomnographyChildrenTherapySleepEarYearsAHIClinicClinicians
2012
Respiratory Event Detection by a Positive Airway Pressure Device
Berry RB, Kushida CA, Kryger MH, Soto-Calderon H, Staley B, Kuna ST. Respiratory Event Detection by a Positive Airway Pressure Device. Sleep 2012, 35: 361-367. PMID: 22379242, PMCID: PMC3274337, DOI: 10.5665/sleep.1696.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaEvents/hrPositive airway pressure devicesApnea indexHypopnea indexPAP devicesRespiratory eventsSleep disorders centerPressure deviceBetter treatment efficacyRespiratory event detectionOxygen desaturationSleep apneaPAP treatmentBland-Altman analysisDisorders CenterPolysomnographyTreatment efficacyAHIInadequate treatmentManual scoringHypopnea detectionTrue negative eventsHrTreatment
2011
Is Laryngeal Descent Associated With Increased Risk for Obstructive Sleep Apnea?
Yamashiro Y, Kryger M. Is Laryngeal Descent Associated With Increased Risk for Obstructive Sleep Apnea? CHEST Journal 2011, 141: 1407-1413. PMID: 22016482, DOI: 10.1378/chest.10-3238.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaAirway lengthSleep apneaJapanese patientsVocal cordsUpper airway lengthLogistic regression analysisMultislice CT scanOSA severityConsecutive patientsUpper airwayRisk factorsCT scanBMIPatientsALVCAHILow laryngeal positionLaryngeal positionCollapsible segmentApneaRegression analysisCordLarynxWomenA Novel Nasal Expiratory Positive Airway Pressure (EPAP) Device for the Treatment of Obstructive Sleep Apnea: A Randomized Controlled Trial
Berry RB, Kryger MH, Massie CA. A Novel Nasal Expiratory Positive Airway Pressure (EPAP) Device for the Treatment of Obstructive Sleep Apnea: A Randomized Controlled Trial. Sleep 2011, 34: 479-485. PMID: 21461326, PMCID: PMC3065258, DOI: 10.1093/sleep/34.4.479.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaPositive airway pressure devicesSleep apneaSham deviceWeek 1Double-blind clinical trialSevere obstructive sleep apneaMonths of treatmentSleep disorders centerEpworth Sleepiness ScalePressure deviceSubjective daytime sleepinessNon-consecutive nightsControlled TrialsMonth 3Sham treatmentClinical trialsDaytime sleepinessITT groupDisorders CenterSleepiness ScaleAHI valuesApneaMedian percentageAHI