Activation of β-catenin signalling leads to temporomandibular joint defects
Wang M, Li S, Xie W, Shen J, Im H, Holz J, Wang M, Diekwisch T, Chen D. Activation of β-catenin signalling leads to temporomandibular joint defects. ECells & Materials 2014, 28: 223-235. PMID: 25340802, PMCID: PMC4288590, DOI: 10.22203/ecm.v028a15.Peer-Reviewed Original ResearchConceptsDouble mutant miceTMJ disordersΒ-cateninMutant miceADAMTS5-/- miceRole of MMP13OA-like phenotypeTemporomandibular joint disordersMG reporter micePotential therapeutic targetDevelopment of TMJTMJ cartilage degenerationHip osteoarthritisTMJ samplesJoint disordersTherapeutic targetReporter miceTransgenic miceCartilage degenerationMiceTMJ cartilageADAMTS5 geneTMJADAMTS5MMP13