2018
Novel Arginine-containing Macrocyclic MMP Inhibitors: Synthesis, 99mTc-labeling, and Evaluation
Ye Y, Toczek J, Gona K, Kim HY, Han J, Razavian M, Golestani R, Zhang J, Wu TL, Ghosh M, Jung JJ, Sadeghi MM. Novel Arginine-containing Macrocyclic MMP Inhibitors: Synthesis, 99mTc-labeling, and Evaluation. Scientific Reports 2018, 8: 11647. PMID: 30076321, PMCID: PMC6076275, DOI: 10.1038/s41598-018-29941-2.Peer-Reviewed Original ResearchConceptsMatrix metalloproteinasesMMP inhibitorsLung tissueTransgenic miceMMP activityHigh radiochemical purityHydroxamate MMP inhibitorsNumber of diseasesTissue remodelingSimilar inhibition potencyPotent inhibitionTherapySpecific bindingInhibitorsMolecular imagingImagingNovel arginineRadiochemical purityTissueHigh radiochemical yieldNew arginine
2014
Applications of Molecular Small-Animal Imaging in Cardiology
Marfatia R, Tavakoli S, Sadeghi M. Applications of Molecular Small-Animal Imaging in Cardiology. 2014, 547-584. DOI: 10.1007/978-1-4939-0894-3_20.Peer-Reviewed Original ResearchMagnetic resonance imagingCardiovascular diseaseImaging modalitiesPrevalence of CVDCourse of diseaseCVD mortality ratesMyocardial perfusion imagingConventional imaging modalitiesTraditional imaging modalitiesPrevention of diseaseDisease activityCoronary angiographyPrognostic informationLeading causeNovel therapiesMortality ratePerfusion imagingTherapeutic interventionsCellular eventsResonance imagingMolecular imaging modalitiesDiseaseEarly detectionTherapyHealth care
2009
Imaging of vascular biology in the heart
Tavakoli S, Sadeghi M. Imaging of vascular biology in the heart. Current Cardiovascular Imaging Reports 2009, 2: 40-49. DOI: 10.1007/s12410-009-0006-9.Peer-Reviewed Original Research