2019
FDG PET imaging of vascular inflammation in post-traumatic stress disorder: A pilot case–control study
Toczek J, Hillmer AT, Han J, Liu C, Peters D, Emami H, Wu J, Esterlis I, Cosgrove KP, Sadeghi MM. FDG PET imaging of vascular inflammation in post-traumatic stress disorder: A pilot case–control study. Journal Of Nuclear Cardiology 2019, 28: 688-694. PMID: 31073848, PMCID: PMC6842076, DOI: 10.1007/s12350-019-01724-w.Peer-Reviewed Original ResearchConceptsFDG-PET imagingPost-traumatic stress disorderFDG signalSystemic inflammationVascular inflammationCardiovascular diseaseBone marrowPET imagingFDG PET/CT imagingPilot case-control studyStress disorderCardiovascular risk factorsInflammatory biomarker levelsHealthy control subjectsPET/CT imagingCase-control studyPositron emission tomography (PET) imagingEmission Tomography ImagingInflammatory biomarkersControl subjectsBlood glucoseRisk factorsBiomarker levelsHealthy controlsProspective group
2015
Interferon-&ggr;–Mediated Allograft Rejection Exacerbates Cardiovascular Disease of Hyperlipidemic Murine Transplant Recipients
Zhou J, Qin L, Yi T, Ali R, Li Q, Jiao Y, Li G, Tobiasova Z, Huang Y, Zhang J, Yun JJ, Sadeghi MM, Giordano FJ, Pober JS, Tellides G. Interferon-&ggr;–Mediated Allograft Rejection Exacerbates Cardiovascular Disease of Hyperlipidemic Murine Transplant Recipients. Circulation Research 2015, 117: 943-955. PMID: 26399469, PMCID: PMC4636943, DOI: 10.1161/circresaha.115.306932.Peer-Reviewed Original ResearchMeSH KeywordsAllograftsAnimalsAortic DiseasesApolipoproteins EAtherosclerosisCardiomyopathiesCardiovascular DiseasesDisease Models, AnimalFemaleGraft RejectionHeart TransplantationHemodynamicsHistocompatibility Antigens Class IIHyperlipidemiasInflammation MediatorsInterferon-gammaLymphocyte ActivationMaleMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutSignal TransductionTh1 CellsVentricular Dysfunction, LeftVentricular Function, LeftConceptsOrgan transplant recipientsCardiovascular diseaseTransplant recipientsEarly-onset cardiovascular diseaseEnd-stage organ failureNative coronary arteriesTh1-type cytokinesT helper cellsHost diseaseAlloimmune responseGraft rejectionAortic stiffeningOrgan failureVentricular dilatationAllogeneic graftsCardiovascular dysfunctionCoronary arteryAortic complianceRisk factorsEffective therapyCardiac contractilityMurine modelAnimal modelsSerological neutralizationImmune system
2011
Age-Related Macular Degeneration and Incident Cardiovascular Disease: The Multi-Ethnic Study of Atherosclerosis
Fernandez AB, Wong TY, Klein R, Collins D, Burke G, Cotch MF, Klein B, Sadeghi MM, Chen J. Age-Related Macular Degeneration and Incident Cardiovascular Disease: The Multi-Ethnic Study of Atherosclerosis. Ophthalmology 2011, 119: 765-770. PMID: 22197438, PMCID: PMC3314126, DOI: 10.1016/j.ophtha.2011.09.044.Peer-Reviewed Original ResearchConceptsAge-related macular degenerationIncident coronary heart diseaseCoronary heart diseaseEarly age-related macular degenerationRisk of CHDCVD eventsMulti-Ethnic StudyRisk factorsMacular degenerationLate age-related macular degenerationNon-AMD groupCVD risk factorsCardiovascular disease eventsIncident cardiovascular diseaseProspective cohort studyHistory of CVDCox regression modelMulti-ethnic cohortMean followCohort studyRetinal photographsClinical followHeart diseaseCardiovascular diseaseDisease events