Integrin-Targeted Imaging of Inflammation in Vascular Remodeling
Razavian M, Marfatia R, Mongue-Din H, Tavakoli S, Sinusas AJ, Zhang J, Nie L, Sadeghi MM. Integrin-Targeted Imaging of Inflammation in Vascular Remodeling. Arteriosclerosis Thrombosis And Vascular Biology 2011, 31: 2820-2826. PMID: 21940943, PMCID: PMC3228522, DOI: 10.1161/atvbaha.111.231654.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsApolipoproteins ECalcium ChlorideCarotid Artery DiseasesCells, CulturedDisease Models, AnimalFemaleFluorescent DyesHumansInflammationIntegrin alphaVIntegrin alphaVbeta3Leukocytes, MononuclearMacrophagesMiceMice, KnockoutPeptides, CyclicRNA, MessengerTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedConceptsVessel wall inflammationCarotid arteryWall inflammationTomography/CT imagingConsiderable macrophage infiltrationLeft carotid arteryMacrophage marker expressionReal-time polymerase chain reactionAdventitial exposureImaging of inflammationAntiinflammatory treatmentVascular eventsMacrophage infiltrationLeft carotidPolymerase chain reactionVascular diseaseContralateral arteryVascular remodelingHigh riskMurine carotid arteriesInflammationArteryFlow cytometryHuman monocytesMRNA expression