A Role for Nuclear Envelope Bridging Complexes in Homology-Directed Repair
Swartz RK, Rodriguez EC, King MC. A Role for Nuclear Envelope Bridging Complexes in Homology-Directed Repair. Molecular Biology Of The Cell 2014, 25: mbc.e13-10-0569. PMID: 24943839, PMCID: PMC4142617, DOI: 10.1091/mbc.e13-10-0569.Peer-Reviewed Original ResearchConceptsDNA double-strand breaksHomology-directed repairRepair of DSBsNumber of genesDouble-strand breaksSame gene productCytoskeleton (LINC) complexLINC complexGenome instabilityATR kinaseGene conversionKms1DSB resectionGene productsDepolymerization of microtubulesCell cycleCytoplasmic microtubulesG2 phaseDNA damageSad1MicrotubulesComplexesNucleoskeletonMTO1Cytoskeleton