Conservative evolution in duplicated genes of the primate Class I ADH cluster
Oota H, Dunn CW, Speed WC, Pakstis AJ, Palmatier MA, Kidd JR, Kidd KK. Conservative evolution in duplicated genes of the primate Class I ADH cluster. Gene 2006, 392: 64-76. PMID: 17204375, DOI: 10.1016/j.gene.2006.11.008.Peer-Reviewed Original ResearchConceptsAlcohol dehydrogenase geneNon-synonymous substitution ratioHetero-dimer formationOverall sequence similarityGene conversionSequence similarityPhylogenetic analysisPrimate evolutionOld World monkeysHigh nucleotide similarityCDNA sequenceDehydrogenase geneChromosome 4Functional constraintsConservative evolutionADH clusterHigh similaritySequence clustersGenesNucleotide similarityLines of evidenceIntron 2Dietary adaptationWorld monkeysFirst split