Should triple-negative breast cancer (TNBC) subtype affect local-regional therapy decision making?
Moran MS. Should triple-negative breast cancer (TNBC) subtype affect local-regional therapy decision making? American Society Of Clinical Oncology Educational Book 2014, e32-6. PMID: 24857120, DOI: 10.14694/edbook_am.2014.34.e32.Peer-Reviewed Original ResearchConceptsTriple-negative breast cancerLocal-regional relapseBreast cancer therapySporadic triple-negative breast cancerBreast cancerEarly-stage triple-negative breast cancerYounger ageAggressive biologic characteristicsBreast conservation approachHER2-positive subgroupContralateral breast cancerWhole breast irradiationDefinitive treatment strategyNegative breast cancer subtypeHypothesis-generating dataPartial breast irradiationBreast cancer subtypesBRCA1 mutation carriersSystemic chemotherapyAdvanced diseaseRandomized trialsGuideline recommendationsLuminal tumorsBreast irradiationTNBC subtypes