2013
Are Breast Cancer Subtypes Prognostic for Nodal Involvement and Associated with Clinicopathologic Features at Presentation in Early-Stage Breast Cancer?
Jones T, Neboori H, Wu H, Yang Q, Haffty BG, Evans S, Higgins S, Moran MS. Are Breast Cancer Subtypes Prognostic for Nodal Involvement and Associated with Clinicopathologic Features at Presentation in Early-Stage Breast Cancer? Annals Of Surgical Oncology 2013, 20: 2866-2872. PMID: 23661183, PMCID: PMC5731457, DOI: 10.1245/s10434-013-2994-6.Peer-Reviewed Original ResearchConceptsNodal involvementClinicopathologic featuresSignificant associationStage I/II diseaseCancer subtypesDistant metastasis-free survivalEarly-stage breast cancerResultsThe study cohortAxillary node involvementBreast-conserving surgeryMetastasis-free survivalUseful prognostic variableBreast cancer subtypesAvailable tissue blocksNode involvementNode positivityNodal metastasisPathological reviewStudy cohortT stageTumor characteristicsTumor histologyTumor sizeProgesterone receptorSurgical assessment
2011
Breast cancers in U.S. residing Indian-Pakistani versus non-Hispanic White women: comparative analysis of clinical-pathologic features, treatment, and survival
Moran MS, Gonsalves L, Goss DM, Ma S. Breast cancers in U.S. residing Indian-Pakistani versus non-Hispanic White women: comparative analysis of clinical-pathologic features, treatment, and survival. Breast Cancer Research And Treatment 2011, 128: 543-551. PMID: 21301957, PMCID: PMC3235412, DOI: 10.1007/s10549-011-1362-0.Peer-Reviewed Original ResearchConceptsBreast conservation surgeryAge-adjusted incidenceBreast cancerAdjuvant radiationNHW womenInvasive diseaseHormone receptor-negative diseaseFemale breast cancer patientsNon-Hispanic white womenPost-mastectomy RTRates of breastClinical-pathologic featuresInvolved lymph nodesPercentage of patientsReceptor-negative diseasePost-mastectomy radiationBreast cancer mortalityBreast cancer patientsLarger tumor sizeYounger median ageRelative survival ratesSignificant differencesMultivariate regression analysisSEER databaseLymph nodes
2008
Long‐term outcomes and clinicopathologic differences of African‐American versus white patients treated with breast conservation therapy for early‐stage breast cancer
Moran MS, Yang Q, Harris LN, Jones B, Tuck DP, Haffty BG. Long‐term outcomes and clinicopathologic differences of African‐American versus white patients treated with breast conservation therapy for early‐stage breast cancer. Cancer 2008, 113: 2565-2574. PMID: 18816610, DOI: 10.1002/cncr.23881.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdenocarcinoma, MucinousAdultAntineoplastic AgentsBlack or African AmericanBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, LobularCohort StudiesCombined Modality TherapyFemaleFollow-Up StudiesHumansLymph NodesLymphatic MetastasisMastectomyNeoplasm Recurrence, LocalNeoplasm StagingPrognosisRadiotherapy DosageSurvival RateTreatment OutcomeWhite PeopleConceptsBreast conservation therapyLymph node recurrenceAA patientsWhite patientsAA womenNode recurrenceConservation therapyClinicopathologic differencesEarly-stage breast cancerChemotherapy/radiotherapyEarly-stage diseaseSurgical margin statusLong-term outcomesP53 expression statusBreast recurrenceOverall survivalIndependent predictorsLocal recurrenceLymph nodesMargin statusClinicopathologic featuresDistant metastasisN classificationMore estrogenBreast cancer