2023
Providing Structured Real-Time Feedback on Postdischarge Outcomes Using Electronic Health Record Data
Zegarek M, Holleck J, Merchant N, Windish D, Hay S. Providing Structured Real-Time Feedback on Postdischarge Outcomes Using Electronic Health Record Data. Southern Medical Journal 2023, 116: 305-311. PMID: 36863053, DOI: 10.14423/smj.0000000000001522.Peer-Reviewed Original ResearchConceptsPostdischarge outcomesTransitions of carePoor patient outcomesInternal medicine residentsPatient outcomesInpatient rotationsMedicine residentsElectronic health record dataTime of dischargeHealth record dataElectronic health recordsDischarge planningFuture practiceFree-text responsesPostintervention surveysHealth recordsRecord dataOutcomesAdditional staffPatientsMedical student participants
2022
Twelve Tips for teaching shared decision making
Zegarek M, Brienza R, Quinn N. Twelve Tips for teaching shared decision making. Medical Teacher 2022, 45: 257-263. PMID: 35793200, DOI: 10.1080/0142159x.2022.2093700.Peer-Reviewed Original Research
2015
Asking for Feedback: Helping Learners Get the Feedback They Deserve
Mariani A, Schumann S, Fromme H, Zegarek M, Swearingen S, Ryan M, Reddy S. Asking for Feedback: Helping Learners Get the Feedback They Deserve. MedEdPORTAL 2015 DOI: 10.15766/mep_2374-8265.10228.Peer-Reviewed Original ResearchUtilizing Feedback: Helping Learners Make Sense of the Feedback They Get
Fromme H, Mariani A, Zegarek M, Swearingen S, Schumann S, Ryan M, Reddy S. Utilizing Feedback: Helping Learners Make Sense of the Feedback They Get. MedEdPORTAL 2015 DOI: 10.15766/mep_2374-8265.10159.Peer-Reviewed Original ResearchBarriers and Facilitators to Effective Feedback: A Qualitative Analysis of Data From Multispecialty Resident Focus Groups
Reddy ST, Zegarek MH, Fromme HB, Ryan MS, Schumann SA, Harris IB. Barriers and Facilitators to Effective Feedback: A Qualitative Analysis of Data From Multispecialty Resident Focus Groups. Journal Of Graduate Medical Education 2015, 7: 214-9. PMID: 26221437, PMCID: PMC4512792, DOI: 10.4300/jgme-d-14-00461.1.Peer-Reviewed Original ResearchConceptsFocus groupsFeedback processesTeacher-learner relationshipImportance of feedbackResident focus groupsGraduate Medical EducationOpen-ended questionsConstant comparative methodTeacher factorsLearner engagementLearning environmentEducational contextFaculty developmentLearner factorsEffective feedbackMedical educationClinical trainingInadequate feedbackFeedback contentTeaching institutionLearnersMajor themesFacilitatorsQualitative analysisResident comfort
2013
Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis
Vasanthakumar A, Lepore JB, Zegarek MH, Kocherginsky M, Singh M, Davis EM, Link PA, Anastasi J, Le Beau MM, Karpf AR, Godley LA. Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis. Blood 2013, 121: 2059-2063. PMID: 23315164, PMCID: PMC3596965, DOI: 10.1182/blood-2012-04-421065.Peer-Reviewed Original ResearchConceptsHaploinsufficient tumor suppressor geneTumor suppressor geneDNA methylationDe novo DNA methyltransferasesSuppressor geneNovo DNA methyltransferasesExpression of DNMT3B7Abnormal DNA methylationDominant negative isoformDifferent molecular mechanismsDNMT3B isoformsDNA methyltransferasesDNA hypermethylationDNMT3B geneAberrant splicingMolecular mechanismsTumor suppressorAbnormal transcriptsMYC/Human cancersGenesDNMT3B7DNMT3BMethylationMYC
2011
Myc-Mediated Lymphomagenesis Is Driven by DNA Methylation Changes Induced by DNMT3B7 Expression and Dnmt3b Heterozygosity
Vasanthakumar A, Lepore J, Zegarek M, Kocherginsky M, Singh M, Godley L. Myc-Mediated Lymphomagenesis Is Driven by DNA Methylation Changes Induced by DNMT3B7 Expression and Dnmt3b Heterozygosity. Blood 2011, 118: 225. DOI: 10.1182/blood.v118.21.225.225.Peer-Reviewed Original ResearchEμ-myc miceDNA methylationGlobal DNA hypermethylationDNA hypermethylationMyc bindsDNA methyltransferasesE-boxDNA methyltransferasePromoter regionCancer cellsDnmt3a/bDNA methylation patternsChromatin immunoprecipitation analysisDNA methylation changesTranscription start siteCo-immunoprecipitation studiesAbnormal DNA methylationBinding of MYCGlobal DNA methylationTransformation of cellsDominant negative isoformNon-transformed cellsDNMT3B isoformsPremature stop codonEukaryotic cells