bakR: uncovering differential RNA synthesis and degradation kinetics transcriptome-wide with Bayesian hierarchical modeling
Vock I, Simon M. bakR: uncovering differential RNA synthesis and degradation kinetics transcriptome-wide with Bayesian hierarchical modeling. RNA 2023, 29: 958-976. PMID: 37028916, PMCID: PMC10275263, DOI: 10.1261/rna.079451.122.Peer-Reviewed Original ResearchMeSH KeywordsBayes TheoremGene Expression ProfilingKineticsRNASequence Analysis, RNASoftwareTranscriptomeConceptsBayesian hierarchical modelingAdvanced statistical modelsHierarchical modelingDifferential expression analysisStatistical modelBayesian analysisRNA synthesisExpression analysisStatistical rigorData setsR packageRNA sequencing dataCellular RNA levelsMethods addressStatistical powerKinetics of RNAImproved analysisSequencing dataModel outperformsUser-friendly softwareModelingSetRNA levelsModelDifferential kinetics