2021
Neonatal Abstinence Syndrome: Management Advances and Therapeutic Approaches
Cheng F, McMillan C, Morrison A, Berkwitt A, Grossman M. Neonatal Abstinence Syndrome: Management Advances and Therapeutic Approaches. Current Addiction Reports 2021, 8: 595-604. DOI: 10.1007/s40429-021-00387-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsNeonatal abstinence syndromeMaternal-infant dyadsNon-pharmacologic interventionsNumber of infantsDevelopment of NASOpioid crisisLong-term neurodevelopmental outcomesNon-pharmacologic careOpioid-exposed infantsProportion of infantsLength of stayPurpose of ReviewInBirth hospitalizationOutpatient managementInpatient managementNeurodevelopmental outcomesClinical presentationAbstinence syndromeVulnerable infantsPharmacologic agentsStrategy warrantsClinical pathwayTherapeutic approachesFunctional assessmentInfants
2017
An Initiative to Improve the Quality of Care of Infants With Neonatal Abstinence Syndrome
Grossman MR, Berkwitt AK, Osborn RR, Xu Y, Esserman DA, Shapiro ED, Bizzarro MJ. An Initiative to Improve the Quality of Care of Infants With Neonatal Abstinence Syndrome. Pediatrics 2017, 139: e20163360. PMID: 28562267, PMCID: PMC5470506, DOI: 10.1542/peds.2016-3360.Peer-Reviewed Original ResearchConceptsNeonatal abstinence syndromeAdverse eventsAbstinence syndromeHospital costsYale-New Haven Children's HospitalTreatment of NASMethadone-exposed infantsLonger hospital stayProportion of infantsAdministration of morphineTransfer of infantsStudy-Act cyclesQuality of careMusculoskeletal disturbancesNonpharmacologic careNonpharmacologic therapiesHospital stayMorphine useOpioid withdrawalChildren's HospitalPostimplementation periodSustained decreaseOutcome measuresInpatient unitMultidisciplinary team