2022
Early Weight Loss Percentile Curves and Feeding Practices in Opioid-Exposed Infants.
Cheng FY, Shabanova V, Berkwitt AK, Grossman MR. Early Weight Loss Percentile Curves and Feeding Practices in Opioid-Exposed Infants. Hospital Pediatrics 2022, 12: 857-866. PMID: 36073203, DOI: 10.1542/hpeds.2021-006137.Peer-Reviewed Original ResearchConceptsNeonatal opioid withdrawal syndromeFeeding practicesWeight loss patternsBirth weightMedian percent weight lossWeight lossMean gestational ageOpioid withdrawal syndromeMean birth weightPercentile curvesRisk of morbidityHours of lifeHealth care useConfidence intervalsOptimal feeding methodNonpharmacologic treatmentsPharmacologic treatmentWithdrawal syndromeGestational agePercent weight lossSingle centerCare useInclusion criteriaInfantsDelivery typeDoes Maternal Incarceration Impact Infants with Neonatal Abstinence Syndrome?
Drago MJ, Shabanova V, Hochreiter D, Grossman M, Mercurio M. Does Maternal Incarceration Impact Infants with Neonatal Abstinence Syndrome? Maternal And Child Health Journal 2022, 26: 1095-1103. PMID: 35088297, DOI: 10.1007/s10995-021-03356-4.Peer-Reviewed Original ResearchConceptsNeonatal abstinence syndromeLength of stayNon-incarcerated womenLine agentsAbstinence syndromeBreast milkMean LOSLonger LOSIncarcerated womenRetrospective cohort studyFirst-line agentsMaternal-infant dyadsSecond-line agentsPrenatal substance exposurePrenatal alcohol useCare of infantsCohort studyFinnegan scoreInfant dischargeLonger hospitalizationSubstance exposureInfantsPoisson regressionMaternal incarcerationAlcohol use
2021
Neonatal Abstinence Syndrome: Management Advances and Therapeutic Approaches
Cheng F, McMillan C, Morrison A, Berkwitt A, Grossman M. Neonatal Abstinence Syndrome: Management Advances and Therapeutic Approaches. Current Addiction Reports 2021, 8: 595-604. DOI: 10.1007/s40429-021-00387-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsNeonatal abstinence syndromeMaternal-infant dyadsNon-pharmacologic interventionsNumber of infantsDevelopment of NASOpioid crisisLong-term neurodevelopmental outcomesNon-pharmacologic careOpioid-exposed infantsProportion of infantsLength of stayPurpose of ReviewInBirth hospitalizationOutpatient managementInpatient managementNeurodevelopmental outcomesClinical presentationAbstinence syndromeVulnerable infantsPharmacologic agentsStrategy warrantsClinical pathwayTherapeutic approachesFunctional assessmentInfantsParent Perspectives on the Eat, Sleep, Console Approach for the Care of Opioid-Exposed Infants
McRae K, Sebastian T, Grossman M, Loyal J. Parent Perspectives on the Eat, Sleep, Console Approach for the Care of Opioid-Exposed Infants. Hospital Pediatrics 2021, 11: 358-365. PMID: 33658244, DOI: 10.1542/hpeds.2020-002139.Peer-Reviewed Original ResearchConceptsNeonatal abstinence syndromeTreatment of infantsParents of infantsNonpharmacologic interventionsNewborn careAbstinence syndromeInfant HospitalMost infantsInpatient unitExpectant mothersInfantsFunction-based assessmentOverall positive experienceHospitalExperiences of parentsMost participantsCareFeelings of guiltSemistructured interviewsSleepParents' perspectivesEmotional supportInterventionEATHypothesis-driven approach
2019
Neonatal abstinence syndrome
Grossman M, Berkwitt A. Neonatal abstinence syndrome. Seminars In Perinatology 2019, 43: 173-186. PMID: 30773241, DOI: 10.1053/j.semperi.2019.01.007.Peer-Reviewed Original ResearchConceptsNeonatal abstinence syndromeAbstinence syndromeIncidence of NASScoring toolNon-pharmacologic interventionsDoses of medicationLong-term outcomesCare of infantsHospital stayMedication usageWithdrawal signsHealthcare systemSyndromeInfantsIncidenceCareScreening approachMedicationsOpioidsRoomingNeonatesStayPathophysiologyDoses
2018
A Novel Approach to Assessing Infants With Neonatal Abstinence Syndrome
Grossman MR, Lipshaw MJ, Osborn RR, Berkwitt AK. A Novel Approach to Assessing Infants With Neonatal Abstinence Syndrome. Hospital Pediatrics 2018, 8: 1-6. PMID: 29263121, DOI: 10.1542/hpeds.2017-0128.Peer-Reviewed Original ResearchConceptsNeonatal abstinence syndromeManagement of infantsTreatment decisionsAbstinence syndromeYale-New Haven Children's HospitalOpioid-exposed infantsLength of stayActual treatment decisionsHealth care systemOpioid treatmentAdverse eventsPharmacologic treatmentPrimary outcomeChildren's HospitalPostnatal treatmentInpatient unitSignificant burdenMorphineInfantsCare systemSyndromeHospitalTreatmentScoresDays
2015
The Utility of Inpatient Rebound Bilirubin Levels in Infants Readmitted After Birth Hospitalization for Hyperbilirubinemia
Berkwitt A, Osborn R, Grossman M. The Utility of Inpatient Rebound Bilirubin Levels in Infants Readmitted After Birth Hospitalization for Hyperbilirubinemia. Hospital Pediatrics 2015, 5: 74-78. PMID: 25646199, DOI: 10.1542/hpeds.2014-0074.Peer-Reviewed Original ResearchConceptsBilirubin levelsLength of stayBirth hospitalizationIndirect hyperbilirubinemiaRebound groupDiscontinuation of phototherapyRetrospective cohort studyManagement of infantsCharacteristics of childrenCohort studySecondary outcomesHospital readmissionPrimary outcomePatient populationSubgroup analysisClinical utilityPatientsInfantsHospitalizationHyperbilirubinemiaPhototherapyReadmissionStayDlPresent study