Inhaled nitric oxide for the postoperative management of pulmonary hypertension in infants and children with congenital heart disease
Bizzarro M, Gross I, Barbosa FT. Inhaled nitric oxide for the postoperative management of pulmonary hypertension in infants and children with congenital heart disease. 2014, 2014: cd005055. PMID: 24991723, PMCID: PMC10728583, DOI: 10.1002/14651858.cd005055.pub3.Peer-Reviewed Original ResearchConceptsMean pulmonary arterial pressurePulmonary hypertensive crisisCongenital heart diseaseLong-term mortalityPulmonary hypertensionHeart rateMethaemoglobin levelsNeurodevelopmental disabilitiesHospital stayArterial pressureNitric oxidePostoperative managementHeart diseaseEfficacy of iNOUse of iNOPulmonary arterial pressureSystemic blood pressureArterial oxygen tensionLength of stayMarkers of toxicityConventional managementHypertensive crisisPostoperative administrationPulmonary vasodilationSecondary outcomesLow‐Dose Intravenous Soybean Oil Emulsion for Prevention of Cholestasis in Preterm Neonates
Levit OL, Calkins KL, Gibson LC, Kelley‐Quon L, Robinson DT, Elashoff DA, Grogan TR, Li N, Bizzarro MJ, Ehrenkranz RA. Low‐Dose Intravenous Soybean Oil Emulsion for Prevention of Cholestasis in Preterm Neonates. Journal Of Parenteral And Enteral Nutrition 2014, 40: 374-382. PMID: 24963025, PMCID: PMC4537394, DOI: 10.1177/0148607114540005.Peer-Reviewed Original ResearchConceptsDays of lifeIntravenous fat emulsionPreterm neonatesPrimary outcomeGestational ageControl groupControl doseFat emulsionDays of PNFull enteral feedsPrevention of cholestasisMajor neonatal morbidityHours of lifeEffective preventive strategiesLow groupHospital stayNeonatal morbidityBaseline characteristicsParenteral nutritionSecondary outcomesEnteral feedsEssential fatty acidsPremature infantsLiver diseaseTotal bilirubin