2024
Measuring practice preference variation for quality improvement in neonatal respiratory care
Healy H, Whitesel E, Mao W, Day C, Murphy T, Song C, Williams P, Brachio S, Cham P, Vartanian R, Chin S, Arora P, Bizzarro M, Sink D, Zupancic J, Gupta M. Measuring practice preference variation for quality improvement in neonatal respiratory care. Journal Of Perinatology 2024, 44: 1001-1008. PMID: 38589537, DOI: 10.1038/s41372-024-01956-w.Peer-Reviewed Original ResearchNeonatal intensive care unitNeonatal respiratory careRespiratory careContinuous positive airway pressureLow birth weight infantsNon-invasive positive pressure ventilationBirth weight infantsPositive airway pressurePositive pressure ventilationIntensive care unitWeight infantsAirway pressureMandatory ventilationInvasive ventilationPressure ventilationCare unitClinical scenariosPressure supportObjectivesThe authorsVentilationQuality improvement effortsApneaNeonatologistsNeonatologyNSIGHT
2015
Clinical and Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit in the Decade following Implementation of an Active Detection and Isolation Program
Nelson MU, Bizzarro MJ, Baltimore RS, Dembry LM, Gallagher PG. Clinical and Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit in the Decade following Implementation of an Active Detection and Isolation Program. Journal Of Clinical Microbiology 2015, 53: 2492-2501. PMID: 26019206, PMCID: PMC4508396, DOI: 10.1128/jcm.00470-15.Peer-Reviewed Original ResearchMeSH KeywordsDNA, BacterialEpidemiological MonitoringFemaleGenetic VariationGenotypeGenotyping TechniquesHumansInfantInfant, NewbornIntensive Care Units, NeonatalMaleMethicillin-Resistant Staphylococcus aureusMolecular EpidemiologyMolecular TypingRetrospective StudiesStaphylococcal InfectionsVirulence FactorsConceptsNeonatal intensive care unitMethicillin-resistant Staphylococcus aureusIntensive care unitMRSA colonizationMolecular epidemiologyCare unitStaphylococcal cassette chromosome mec type IIAccessory gene regulator (agr) groupsMRSA colonization rateToxic shock syndrome toxinAgr group 1Exfoliative toxin AStaphylococcus aureusPotential virulence factor genesVirulence factor genesMRSA infectionSignificant morbidityClinical differencesPatient daysPulsed-field gel electrophoresisToxin AUSA300 strainGroup 1Continued vigilanceInfectionNeonatal Sepsis 2004-2013: The Rise and Fall of Coagulase-Negative Staphylococci
Bizzarro MJ, Shabanova V, Baltimore RS, Dembry LM, Ehrenkranz RA, Gallagher PG. Neonatal Sepsis 2004-2013: The Rise and Fall of Coagulase-Negative Staphylococci. The Journal Of Pediatrics 2015, 166: 1193-1199. PMID: 25919728, PMCID: PMC4413005, DOI: 10.1016/j.jpeds.2015.02.009.Peer-Reviewed Original ResearchConceptsEarly-onset sepsisLate-onset sepsisNeonatal intensive care unitCoagulase-negative staphylococciIntensive care unitCare unitLevel IV neonatal intensive care unitEpisodes of sepsisLow birth weightInfection prevention initiativesInfection prevention effortsPercent of casesGroup B streptococciHospital courseSepsis episodesMost infantsBirth weightCommon organismB streptococciSepsisOutcome dataAdditional surveillancePrevention effortsStudy periodInfants
2014
Methicillin-resistant Staphylococcus aureus : impact on care in the neonatal unit
Nelson M, Bizzarro M, Gallagher P. Methicillin-resistant Staphylococcus aureus : impact on care in the neonatal unit. 2014, 41-61. DOI: 10.2217/ebo.13.571.Peer-Reviewed Original ResearchNeonatal intensive care unitMethicillin-resistant Staphylococcus aureusMRSA transmissionTreatment of MRSAIntensive care unitAppropriate treatment regimensMRSA colonizationNeonatal morbidityMRSA acquisitionCare unitIll infantsNeonatal unitSignificant morbidityTreatment regimensRisk factorsMRSA strainsPrevention strategiesNeonatesInfectionPervasive pathogenEarly detectionMorbidityStaphylococcus aureusInfantsEpidemiologyEar drainage and the role of sepsis evaluations in the neonatal intensive care unit
Khattab M, Cannon‐Heinrich C, Bizzarro MJ. Ear drainage and the role of sepsis evaluations in the neonatal intensive care unit. Acta Paediatrica 2014, 103: 732-736. PMID: 24635016, PMCID: PMC4320968, DOI: 10.1111/apa.12636.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitIntensive care unitEar drainageSepsis evaluationCare unitTape removalMedian gestational ageExternal auditory canalGestational ageAuditory canalInflammatory processUnnecessary interventionsAnti-adhesive productDrainageInterventionEarOnsetBirthweightAdmissionCasesEvaluationWeeks
2013
Temporal quantification of oxygen saturation ranges: an effort to reduce hyperoxia in the neonatal intensive care unit
Bizzarro MJ, Li FY, Katz K, Shabanova V, Ehrenkranz RA, Bhandari V. Temporal quantification of oxygen saturation ranges: an effort to reduce hyperoxia in the neonatal intensive care unit. Journal Of Perinatology 2013, 34: 33-38. PMID: 24071904, DOI: 10.1038/jp.2013.122.Peer-Reviewed Original ResearchConceptsSevere ROPRetinopathy of prematurityNeonatal intensive care unitIntensive care unitCare unitMultivariate analysisBronchopulmonary dysplasia/deathTarget saturation rangePost-intervention evaluationPreterm neonatesOxygen saturationStaff educationSurgeryInfantsMultidisciplinary groupSignificant reductionHyperoxiaDeathExposureSignal extraction technologyMorbidityPrematurityRetinopathyNeonatesNeutrophil CD64 with Hematologic Criteria for Diagnosis of Neonatal Sepsis
Streimish I, Bizzarro M, Northrup V, Wang C, Renna S, Koval N, Li FY, Ehrenkranz RA, Rinder HM, Bhandari V. Neutrophil CD64 with Hematologic Criteria for Diagnosis of Neonatal Sepsis. American Journal Of Perinatology 2013, 31: 021-030. PMID: 23456906, DOI: 10.1055/s-0033-1334453.Peer-Reviewed Original ResearchConceptsCulture-proven sepsisClinical sepsisNeutrophil CD64CD64 indexNeonatal sepsisHematologic criteriaSingle-centre neonatal intensive care unitEarly-onset clinical sepsisNeonatal intensive care unitNeutrophil CD64 indexProspective observational cohortAbsolute neutrophil countNormal birth weightIntensive care unitAbsolute band countNegative predictive valueAdditional markersSepsis evaluationNeutrophil countObservational cohortCare unitBirth weightHematologic parametersSepsisCD64
2011
Risk factors for necrotizing enterocolitis totalis: a case–control study
Thompson A, Bizzarro M, Yu S, Diefenbach K, Simpson B, Moss R. Risk factors for necrotizing enterocolitis totalis: a case–control study. Journal Of Perinatology 2011, 31: 730-738. PMID: 21436786, DOI: 10.1038/jp.2011.18.Peer-Reviewed Original ResearchConceptsCase-control studyGestational ageEnterocolitis totalisBreast milkOdds ratioNewborn Special Care UnitYale-New Haven Children's HospitalRetrospective case-control studyFull enteral feedsGroup II controlsOccurrence of NECRisk of NECDate of diagnosisDays of diagnosisConfidence intervalsSpecial care unitsDays of lifePreterm patientsStudy patientsDate of birthPreterm neonatesCare unitChildren's HospitalGastrointestinal malformationsClinical events